Developmental & Stem Cell Biology

BMS is home to numerous faculty members with research programs focused on fundamental questions in Developmental and Stem Cell Biology. In addition to the focus area within BMS, a distinct Graduate Program in Developmental and Stem Cell Biology exists for those applicants who are committed to those topics. This program has a more focused curriculum including coursework, seminars, and journal clubs specific to Developmental and Stem Cell Biology. The BMS program maintains a more interdisciplinary curriculum, integrating multiple distinct focus areas with an overarching emphasis on biomedically relevant questions.


Most Developmental and Stem Cell Biology faculty members have appointments in both programs. Key topics of investigation among the faculty include cellular specification and differentiation, organogenesis, tissue morphogenesis and regeneration, and cell-cell signaling during development. A variety of model systems are used to pursue relevant topics in Developmental and Stem Cell Biology, including worms, flies, fish, chickens, mice, and human-derived tissues and cells.

 

Participating Faculty

Andrew Leavitt, MD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
None
Research Summary: 
Hematopoietic Stem Cells and Megakaryocytopoiesis

Jingjing Li, PhD

Primary Thematic Area: 
Human Genetics
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Large-scale analysis of disease genomes by integrating multi-omics data, evolutionary insights, health records, and digitized clinical traits from imaging and wearable sensor readouts.

Daniel Lim, MD, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Chromatin regulators and long noncoding RNAs (lncRNAs) in neural development and disease

Tippi MacKenzie, MD

Primary Thematic Area: 
Immunology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Stem cell transplantation, maternal-fetal tolerance, and fetal molecular therapies

Emin Maltepe, MD, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
The Regulation of Cell Fate by Oxygen and Mitochondria

Ralph Marcucio, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
None
Research Summary: 
Craniofacial development, evolutionary biology, trauma, bone repair, angiogenesis

Aras Mattis, MD, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
Regulation of hepatic development, metabolism, and paths towards cancer.
Mentorship Development: 

4/12/19    Acknowleding and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab (Parnassus)
12/12/19    ACRA: Setting Training Expectations for Trainees on the Academic Career Track (1.5 hours)
10/20/20    Gathering in Community: a Training for Faculty and Staff

Thea Mauro, MD

Primary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Ionic Fluxes Control Keratinocyte Adhesion, Differentiation and Secretion

Michael Mcmanus, PhD

Primary Thematic Area: 
Human Genetics
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Noncoding RNAs - the Dark Matter of the Genome
Mentorship Development: 

4/29/19 - Sharpening your Mentoring Skills (SyMS) 
5/26/20 - Effective Strategies for IDPs for Partial Resumption of Lab Research
11/10/20 - Optimizing the Efficiency of Your Lab
2/16/21 - Three Truths and Three Tries: Facing and Overcoming Critical Social Justice Challenges at the Micro, Mezzo, and Macro Levels
5/2021 - Sharpening your Mentoring Skills (SyMS) 

Synthia Mellon, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Neurobiology
Research Summary: 
Developmental Regulation, Molecular Biology and Novel Actions of Steroid/Neurosteroid Synthesis

Takashi Mikawa, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Vascular & Cardiac Biology
Research Summary: 
Developmental Regulation of Organogenesis
Mentorship Development: 

4/26/19    Sharpening your Mentoring Skills (SyMS) with Sharon Milgram (Mission Bay)
2/18/21    Three Truths and Three Tries: Facing and Overcoming Critical Social Justice Challenges at the Micro, Mezzo, and Macro Levels

Keith Mostov, MD, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
How the most common organs, epithelial tubes, are formed and regenerated.

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