Barbara Panning, PhD

Professor
Department of Biochemistry and Biophysics
[email protected]
+1 415 514-0448
Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
The Panning lab studies mammalian stem cell epigenetics, focusing on X-inactivation and chromatin modifiers.
Mentorship Development: 

4/26/19    Sharpening your Mentoring Skills (SyMS) with Sharon Milgram (Mission Bay)
10/20/20    Gathering in Community: a Training for Faculty and Staff

Publications: 

The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate.

bioRxiv : the preprint server for biology

Marin H, Simental E, Allen C, Martin E, Panning B, Al-Sady B, Buchwalter A

X chromosome factor Kdm6a enhances cognition independent of its demethylase function in the aging XY male brain.

The journals of gerontology. Series A, Biological sciences and medical sciences

Shaw CK, Abdulai-Saiku S, Marino F, Wang D, Davis EJ, Panning B, Dubal DB

A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease.

Science translational medicine

Davis EJ, Broestl L, Abdulai-Saiku S, Worden K, Bonham LW, Miñones-Moyano E, Moreno AJ, Wang D, Chang K, Williams G, Garay BI, Lobach I, Devidze N, Kim D, Anderson-Bergman C, Yu GQ, White CC, Harris JA, Miller BL, Bennett DA, Arnold AP, De Jager PL, Palop JJ, Panning B, Yokoyama JS, Mucke L, Dubal DB

OGT binds a conserved C-terminal domain of TET1 to regulate TET1 activity and function in development.

eLife

Hrit J, Goodrich L, Li C, Wang BA, Nie J, Cui X, Martin EA, Simental E, Fernandez J, Liu MY, Nery JR, Castanon R, Kohli RM, Tretyakova N, He C, Ecker JR, Goll M, Panning B

Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program.

Proceedings of the National Academy of Sciences of the United States of America

Kime C, Sakaki-Yumoto M, Goodrich L, Hayashi Y, Sami S, Derynck R, Asahi M, Panning B, Yamanaka S, Tomoda K