2024-25 Journal Club Schedule
Journal Club Co-Directors: Elizabeth Crouch, MD, PhD and Julia Carnevale, MD
Day/Time: Thursdays, 12:10-1:00 p.m. except as noted
Location:In person on the Parnassus campus, with a livestream/Zoom option to Mission Bay as well. The Zoom link will be sent out with the email reminder sent to the BMS listservs. Please contact Meredith Miner if you are not already on one of our listservs.
Links to previous livestreams and recorded video are in the sidebar.
See the BMS Journal Club Archives in the right sidebar for past journal club descriptions and recordings.
September 12, 2024
Isha Jain (faculty)
"Sharing is Caring: The Therapeutic Potential of Mitochondrial Transfer"
Nakai, R., Varnum, S., Field, R.L. et al. Mitochondria transfer-based therapies reduce the morbidity and mortality of Leigh syndrome. Nat Metab (2024). https://doi.org/10.1038/s42255-024-01125-5
Rebecca Chu (student)
“Keto Diet: Fad or Fab?”
Acuña-Catalán, D. et al. Ketogenic diet administration later in life improves memory by modifying the synaptic cortical proteome via the PKA signaling pathway in aging mice, Cell Reports Medicine 5, (2024).
Coaches: Saul Villeda, PhD
Moderator: Tasha Tsao
September 19, 2024
Jose Angel Nicolas-Avila (faculty)
" A sneak peek to the bright side of immune cells: Microglia protect against age-associated brain pathologies"
Munro, David A.D. et al. Microglia protect against age-associated brain pathologies. Neuron, Volume 112, Issue 16, 2732 - 2748.e8
Mackenzie Roberts (student)
“B(00)7-H4 - Giving T Cells a ‘License to Kill’ ”
Yu, Jiali, et al. “Progestogen-Driven B7-H4 Contributes to Onco-Fetal Immune Tolerance.” Cell, vol. 187, no. 17, Aug. 2024, pp. 4713-4732.e19. www.cell.com, https://doi.org/10.1016/j.cell.2024.06.012.
Coaches: Adrian Erlebacher, MD, PhD & Betsy Crouch, MD, PhD
September 26, 2024
Peter Beernink (faculty)
"Do meningococcal outer membrane vesicle vaccines protect against gonorrhea?"
Molina JM, et al.; ANRS 174 DOXYVAC Study Group. Doxycycline prophylaxis and meningococcal group B vaccine to prevent bacterial sexually transmitted infections in France (ANRS 174 DOXYVAC): a multicentre, open-label, randomised trial with a 2 × 2 factorial design. Lancet Infect Dis. 2024 May 23:S1473-3099(24)00236-6. doi: 10.1016/S1473-3099(24)00236-6. PMID: 38797183.
Joy Okoro (student)
“CD4+ T Cells: The Surge Protectors of Mtb Immunity”
Bromley et al. (2024) Cell Immunity "CD4+ T cells re-wire granuloma cellularity and regulatory networks to promote immunomodulation following Mtb reinfection" https://www.cell.com/immunity/fulltext/S1074-7613(24)00375-3
Coaches: Sara Suliman, PhD, MPH & Joel Ernst, MD
Moderator: Lily Zemelko
October 3, 2024
Dena Dubal (faculty)
"Slow Down: IL11 and Extending Lifespan"
Widjaja, A.A., Lim, WW., Viswanathan, S. et al. Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature 632, 157–165 (2024). https://doi.org/10.1038/s41586-024-07701-9
Jose Gomez (student)
"It was the best of times, it was the worst of times"
Kim, Tae Wan. “TNF-NF-ΚB-P53 Axis Restricts in Vivo Survival of HPSC- ...” Cell, 11 July 2024, www.cell.com/cell/fulltext/S0092-8674(24)00575-0.
Coaches: Tomasz Nowakowski, PhD & Betsy Crouch, MD, PhD
Moderator: Jose Gomez
October 10, 2024
Arun Wiita (faculty)
"Taking evasive action: cloaking allogeneic CAR-T and CAR-NK cells from host rejection via adhesion ligand deletion"
Hammer Q, et al. Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies. Cell Stem Cell. 2024 Sep 5;31(9):1376-1386.e8. doi: 10.1016/j.stem.2024.06.011.
Claire Havig (student)
TBD
Lee, C.S., Chen, S., Berry, C.T. et al. Fate induction in CD8 CAR T cells through asymmetric cell division. Nature (2024). https://doi.org/10.1038/s41586-024-07862-7
Coaches: Greg Allen, MD, PhD & TBD
Moderator: Rachel Prorok
October 17, 2024
Peng He (faculty)
“Mapping the total transcriptome in space for FFPE tissues”
Bai, Zhiliang, et al. "Spatially exploring RNA biology in archival formalin-fixed paraffin-embedded tissues." Cell (2024).
Harnoor Virk (student)
TBD
Sáez-Cirión, Asier et al. “Sustained HIV remission after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells.” Nature medicine, 10.1038/s41591-024-03277-z. 2 Sep. 2024, doi:10.1038/s41591-024-03277-z
Coaches: Nadia Roan, PhD & Oscar Aguilar, PhD
Moderator: Celeste Garza
October 24, 2024
Trevor Fidler (faculty)
TBD
Takaoka, M., Zhao, X., Lim, H.Y. et al. Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis. Nature (2024). https://doi.org/10.1038/s41586-024-07993-x
Charles Shen (student)
TBD
Gogoi, M., Clark, P.A., Ferreira, A.C.F. et al. ILC2-derived LIF licences progress from tissue to systemic immunity. Nature 632, 885–892 (2024). https://doi.org/10.1038/s41586-024-07746-w
Moderator: Zachary Holmes
October 31, 2024
David Raleigh (faculty)
"Semi-spiky tumor cells aren’t that scary"
Curry RN, Ma Q, McDonald MF, Ko Y, Srivastava S, Chin PS, He P, Lozzi B, Athukuri P, Jing J, Wang S, Harmanci AO, Arenkiel B, Jiang X, Deneen B, Rao G, Serin Harmanci A. "Integrated electrophysiological and genomic profiles of single cells reveal spiking tumor cells in human glioma." Cancer Cell. 2024 Oct 14;42(10):1713-1728.e6. doi: 10.1016/j.ccell.2024.08.009.
Moderator: Harnoor Virk
November 7, 2024
Alejandro Sweet-Cordero (faculty)
"In vivo Crispr screens to identify genes involved in tumor-microenvironment interactions"
Su, P., Liu, Y., Chen, T. et al. In vivo CRISPR screens identify a dual function of MEN1 in regulating tumor–microenvironment interactions. Nat Genet 56, 1890–1902 (2024). https://doi.org/10.1038/s41588-024-01874-9
Zachary Holmes (student)
TBD
Tsuji, T., Tolstikov, V., Zhang, Y. et al. Light-responsive adipose-hypothalamus axis controls metabolic regulation. Nat Commun 15, 6768 (2024). https://doi.org/10.1038/s41467-024-50866-0
Coaches: Roarke Kamber, PhD, Saul Villeda, PhD
Moderator: Charles Shen
November 14, 2024
TBD (faculty)
Lily Zemelko (students)
TBD
Wang K., et al. Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells. Cancer Cell. 2024 Sep 9;42(9):1582-1597.e10. doi: 10.1016/j.ccell.2024.08.007.
Coaches: Rachel Rutishauser, MD, PhD & Matt Spitzer, PhD
Moderator: Julia McBride
November 21, 2024
"Glands-plaining our way through lineage fidelity"
Celeste Garza (student)
Coaches: Sara Suliman, PhD, MPH and Joel Ernst, MD
Moderator: Claire Havig
December 12, 2024
Trishna Patel (student)
Coaches: Roarke Kamber, PhD and Karin Pelka, PhD
Nikhita Kirthivasan (student)
"Diving behind the scenes of the first itch"
Coaches: Jason Cyster, PhD and Roberto Ricardo-Gonzalez, MD, PhD
Moderator: Julia McBride
Location: HSW-302, Parnassus & MH-1405, Mission Bay
January 9, 2025
Madeline McCanne (student)
"Systematic perturbation screens identify regulators of inflammatory macrophage states and a role for TNF mRNA m6A modification"
Coaches: Michael McManus, PhD and John Liu, MD, PhD
Sangeetha Ramachandran (student)
Coaches: Cathryn Cadwell, MD, PhD
Moderator: Lauren Tabor & Nikhita Kirthivasan
Location: HSW-302, Parnassus & MH-1405, Mission Bay
January 16, 2025
Simon Wong (student)
TBD
Coaches: Roarke Kamber, PhD and Ari Molofsky, MD, PhD
Michelle Seeler (student)
"How Fallopian Tube Rheology Drives Cilia Formation and Function"
Coaches: Helen Willsey
Moderator: Clara Kochendoerfer & Madeline McCanne
Location: HSW-302, Parnassus & MH-1405, Mission Bay
January 23, 2025
Paul Leclerc (student)
TBD
Coaches: Alexis Combes, PhD and Karin Pelka, PhD
Caitlyn Dang (student)
"From Powerhouse to Problem"
Coaches: Isha Jain, PhD and Jose Angel Nicolas Avila, PhD
Moderator: Eva Gillis-Buck & Trishna Patel
Location: HSW-302, Parnassus & MH-1405, Mission Bay
January 30, 2025
Emily Chen (student)
TBD
Helen Huynh (student)
TBD
Coaches: Isha Jain and Michael Alexanian
Moderators: Karla DeLucas and Cassandra Martinez
Location: HSW-302, Parnassus & MH-1405, Mission Bay
February 6, 2025
Andrew Pan (student)
TBD
Eva Gillis-Buck (student)
TBD
Moderator: Courtney Tamaki & Liz Arouge
Location: HSW-302, Parnassus & MH-1405, Mission Bay
February 13, 2025
Cassandra Martinez (studnet)
TBD
Rachel Prorok (student)
TBD
Moderator: Joy Okoro & Shania Garrison
Location: HSW-302, Parnassus & MH-1405, Mission Bay
February 20, 2025
Tasha Tsao (student)
TBD
Karla DeLucas (student)
TBD
Moderator: Sangeetha Ramachandran & Monet Yuan
Location: HSW-302, Parnassus & MH-1405, Mission Bay
February 27, 2025
Christina Ekstrand (student)
TBD
Alvin Ha (student)
TBD
Moderator: Rebecca Chu & Becca Fulthorpe
Location: HSW-302, Parnassus & MH-1405, Mission Bay
March 6, 2025
Joseph Moreno (student)
TBD
Anthony Khalifeh (studeny)
TBD
Moderator: Paul Leclerc & Daniel Brody
Location: HSW-302, Parnassus & MH-1405, Mission Bay
March 13, 2025
Ananya Krishnapura (student)
TBD
Patrick Kennedy (student)
TBD
Moderator: Emily Chen & Simon Wong
Location: HSW-302, Parnassus & MH-1405, Mission Bay
March 20, 2025
Courtney Tamaki (student)
TBD
Clara Kochendoerfer (student)
TBD
Moderator: Christina Ekstrand & Alvin Ha
Location: HSW-302, Parnassus & MH-1405, Mission Bay
March 27, 2025
Lauren Tabor (student)
TBD
Joy Okoro (student)
TBD
Moderator: Joseph Moreno & Anthony Khalifeh
Location: HSW-302, Parnassus & MH-1405, Mission Bay
April 3, 2025
Moderator: Ananya Krishnapura & Patrick Kennedy
April 10, 2025
Moderator: Michelle Seeler & Helen Huynh
April 17, 2025
Moderator: Caitlyn Dang & Angel Ruvalcaba
April 25, 2025
Moderator: Shriley Bi & Arren Ramsey
May 1, 2025
Moderator: Mandy Buck & Gwen Cusing
May 8, 2025
Moderator: Andy Davis & Jose Cedano
May 15, 2025
Moderator: Jeremy Libang & Dario Tagliaferri
May 22, 2025
Moderator: Dmytro Dorovskyi & Viva Vykunta
May 29, 2025
Moderator: Liana Beld & Julia Johannsen