Developmental & Stem Cell Biology

BMS is home to numerous faculty members with research programs focused on fundamental questions in Developmental and Stem Cell Biology. In addition to the focus area within BMS, a distinct Graduate Program in Developmental and Stem Cell Biology exists for those applicants who are committed to those topics. This program has a more focused curriculum including coursework, seminars, and journal clubs specific to Developmental and Stem Cell Biology. The BMS program maintains a more interdisciplinary curriculum, integrating multiple distinct focus areas with an overarching emphasis on biomedically relevant questions.


Most Developmental and Stem Cell Biology faculty members have appointments in both programs. Key topics of investigation among the faculty include cellular specification and differentiation, organogenesis, tissue morphogenesis and regeneration, and cell-cell signaling during development. A variety of model systems are used to pursue relevant topics in Developmental and Stem Cell Biology, including worms, flies, fish, chickens, mice, and human-derived tissues and cells.

 

Participating Faculty

Bjoern Schwer, MD, PhD

Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Genomic instability and DNA repair in neural cells

Licia Selleri, PhD, MD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Human Genetics
Research Summary: 
Genetic and regulatory control of morphogenesis in embryonic development, evolution, and disease

Yin Shen, PhD

Primary Thematic Area: 
Human Genetics
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Functional genomics, gene regulation, 3D chromatin architecture, and human diseases

Joseph Shieh, MD, PhD

Primary Thematic Area: 
Human Genetics
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Genomic Determinants in Human Developmental Disorders

Julie Sneddon, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
The niche in pancreatic development and disease

Deepak Srivastava, MD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Human Genetics
Research Summary: 
Molecular and Genetic Dissection of Cardiogenesis and its role in human disease

E. Alejandro Sweet-Cordero, MD

Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
We use genetics and functional genomics to study cancer biology in mouse and human systems. Current emphasis is on lung cancer and pediatric sarcomas.

Erik Ullian, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
My laboratory is interested in the interactions between neurons and glia that are required for the proper development and function of the nervous system.

Saul Villeda, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Mechanisms of Brain Aging and Rejuvenation

Thiennu Vu, MD, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
The regulation of lung vascularization and development

Bruce Wang, MD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
We study how the different cell types in the liver, in particular the hepatocyte, are generated during development, patterned and maintained during adulthood, and regenerate after injury.

Rong Wang, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Vascular & Cardiac Biology
Research Summary: 
Molecular Regulation of Arterial-Venous Programming in Development and Disease

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