Developmental & Stem Cell Biology

BMS is home to numerous faculty members with research programs focused on fundamental questions in Developmental and Stem Cell Biology. In addition to the focus area within BMS, a distinct Graduate Program in Developmental and Stem Cell Biology exists for those applicants who are committed to those topics. This program has a more focused curriculum including coursework, seminars, and journal clubs specific to Developmental and Stem Cell Biology. The BMS program maintains a more interdisciplinary curriculum, integrating multiple distinct focus areas with an overarching emphasis on biomedically relevant questions.


Most Developmental and Stem Cell Biology faculty members have appointments in both programs. Key topics of investigation among the faculty include cellular specification and differentiation, organogenesis, tissue morphogenesis and regeneration, and cell-cell signaling during development. A variety of model systems are used to pursue relevant topics in Developmental and Stem Cell Biology, including worms, flies, fish, chickens, mice, and human-derived tissues and cells.

 

Participating Faculty

Corey Harwell, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Molecular regulation of neural cell fate and circuit assembly

Peng He, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Human Genetics
Research Summary: 
Single-cell and spatial transcriptomics and multiomics; computational biology; gene regulation in cell fate decision

Matthias Hebrok, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Investigate the mechanisms underlying pancreatic diseases, including diabetes and pancreatic cancer, in order to gain novel insights that can be translated into therapeutic treatments for patients suffering from these diseases.
Mentorship Development: 

12/19/19 ACRA: Setting training expectations for trainees on the academic career track

Edward Hsiao, MD, PhD

Primary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Hormonal and genetic regulation of human skeletal disease
Mentorship Development: 

4/30/20    Mental Health in a Pandemic: Q&A for Faculty
2/16/21    Three Truths and Three Tries: Facing and Overcoming Critical Social Justice Challenges at the Micro, Mezzo, and Macro Levels

Yadong Huang, MD, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Molecular Mechanisms and Therapeutic Strategies of Neurodegenerative Diseases
Mentorship Development: 

5/2021 - Sharpening your Mentoring Skills (SyMS)

Guo Huang, PhD

Primary Thematic Area: 
Vascular & Cardiac Biology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Comparative study of organ development and regeneration

Eric Huang, MD, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Molecular Mechanisms Controlling Neuronal and Neurovascular Development
Mentorship Development: 

9/11/20    Mentoring Across Differences

Erica Hutchins, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Neurobiology
Research Summary: 
Post-transcriptional control of cell fate choices during development and disease

Holly Ingraham, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Mechanisms of Hormone Action in Organ Development and Disease

Yuh Nung Jan, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
We are interested in the mechanisms underlying normal development of the nervous system and use that information to gain insights about the cellular and molecular causes of neurological disorders, and the regulation of axon and dendrite regeneration.

Leanne Jones, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Defining conserved mechanisms regulating stem cell behavior and how these are altered with age and in response to chronic or acute changes in metabolism.

Ophir Klein, PhD, MD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Human Genetics
Research Summary: 
Developmental genetics of organ formation and regeneration

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