Developmental & Stem Cell Biology

BMS is home to numerous faculty members with research programs focused on fundamental questions in Developmental and Stem Cell Biology. In addition to the focus area within BMS, a distinct Graduate Program in Developmental and Stem Cell Biology exists for those applicants who are committed to those topics. This program has a more focused curriculum including coursework, seminars, and journal clubs specific to Developmental and Stem Cell Biology. The BMS program maintains a more interdisciplinary curriculum, integrating multiple distinct focus areas with an overarching emphasis on biomedically relevant questions.


Most Developmental and Stem Cell Biology faculty members have appointments in both programs. Key topics of investigation among the faculty include cellular specification and differentiation, organogenesis, tissue morphogenesis and regeneration, and cell-cell signaling during development. A variety of model systems are used to pursue relevant topics in Developmental and Stem Cell Biology, including worms, flies, fish, chickens, mice, and human-derived tissues and cells.

 

Participating Faculty

Yadong Huang, MD, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Molecular Mechanisms and Therapeutic Strategies of Neurodegenerative Diseases
Mentorship Development: 

5/2021 - Sharpening your Mentoring Skills (SyMS)

Guo Huang, PhD

Primary Thematic Area: 
Vascular & Cardiac Biology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Comparative study of organ development and regeneration

Erica Hutchins, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Neurobiology
Research Summary: 
Post-transcriptional control of cell fate choices during development and disease

Holly Ingraham, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Mechanisms of Hormone Action in Organ Development and Disease

Yuh Nung Jan, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
We are interested in the mechanisms underlying normal development of the nervous system and use that information to gain insights about the cellular and molecular causes of neurological disorders, and the regulation of axon and dendrite regeneration.

Leanne Jones, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Defining conserved mechanisms regulating stem cell behavior and how these are altered with age and in response to chronic or acute changes in metabolism.

Ophir Klein, PhD, MD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Human Genetics
Research Summary: 
Developmental genetics of organ formation and regeneration

Sarah Knox, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
None
Research Summary: 
Mechanisms Guiding Epithelial Organogenesis and Tissue Regeneration
Mentorship Development: 

4/12/19  Acknowleding and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab (Parnassus)
5/2021 - Sharpening your Mentoring Skills (SyMS)

Scott Kogan, MD

Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Cooperating Events in Myeloid Leukemogenesis and Their Reversal
Mentorship Development: 

6/10/20    Tools and Tips for Virtual Learning
2/16/21    Three Truths and Three Tries: Facing and Overcoming Critical Social Justice Challenges at the Micro, Mezzo, and Macro Levels

Terumi Kohwi-Shigematsu, PhD

Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Genome organizer function in cancer metastasis and in cell development

Arnold Kriegstein, MD, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Neurobiology
Research Summary: 
Neural Stem Cells and Embryonic Cortical Development
Mentorship Development: 

4/29/19    Sharpening your Mentoring Skills (SyMS) with Sharon Milgram (Parnassus)    
9/11/20    Mentoring Across Differences
2/16/21    Three Truths and Three Tries: Facing and Overcoming Critical Social Justice Challenges at the Micro, Mezzo, and Macro Levels    

Diana Laird, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Genetic and environmental mechanisms of germline development
Mentorship Development: 

4/30/20    Mental Health in a Pandemic: Q&A for Faculty
5/26/20    Effective Strategies for IDPs for Partial Resumption of Lab Research
11/10/20    Optimizing the Efficiency of Your Lab

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