Developmental & Stem Cell Biology

BMS is home to numerous faculty members with research programs focused on fundamental questions in Developmental and Stem Cell Biology. In addition to the focus area within BMS, a distinct Graduate Program in Developmental and Stem Cell Biology exists for those applicants who are committed to those topics. This program has a more focused curriculum including coursework, seminars, and journal clubs specific to Developmental and Stem Cell Biology. The BMS program maintains a more interdisciplinary curriculum, integrating multiple distinct focus areas with an overarching emphasis on biomedically relevant questions.


Most Developmental and Stem Cell Biology faculty members have appointments in both programs. Key topics of investigation among the faculty include cellular specification and differentiation, organogenesis, tissue morphogenesis and regeneration, and cell-cell signaling during development. A variety of model systems are used to pursue relevant topics in Developmental and Stem Cell Biology, including worms, flies, fish, chickens, mice, and human-derived tissues and cells.

 

Participating Faculty

Robert Nissenson, PhD

Primary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Signal Transduction Mechanisms in Bone Cell Differentiation and Function

Tomasz Nowakowski, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Developmental origins of cellular diversity in the nervous system. Molecular and cellular mechanisms of cortical development.

Todd Nystul, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
Epithelial stem cells and cancer

Barbara Panning, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
The Panning lab studies mammalian stem cell epigenetics, focusing on X-inactivation and chromatin modifiers.

Feroz Papa, MD, PhD

Primary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Protein misfolding diseases and novel therapies

Tien Peng, MD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Vascular & Cardiac Biology
Research Summary: 
Contribution of mesenchymal niche to homeostasis, repair, and aging

Anders Persson, PhD

Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Our research focuses on understanding how oncogenic events can transform stem cell and progenitor populations in the brain, and whether the cell of origin is reflected in resulting tumors.

Katie Pollard, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Virology & Microbial Pathogenesis
Research Summary: 
Statistical and Computational Methods for the Analysis of Massive Genomic Datasets

Alex Pollen, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
We study how genetic changes that accumulated over the last 6 million years of human evolution influence specialized features of brain development using single cell genomics, cerebral organoid models of ape brain development, and genome engineering.

Jason Pomerantz, MD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Mesenchymal tissue regeneration

David Raleigh, PhD, MD

Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
We are interested in understanding how developmental signaling pathway drive the growth of brain tumors.

Jeremy Reiter, MD, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Signaling at the Primary Cilium, the Cell's Antenna

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