Jason Pomerantz, MD

Associate Professor
Department of Surgery
Research Overview: 

Our laboratory studies basic and translational aspects of tissue regeneration. With foundations in muscle and cancer biology, we are investigating regenerative mechanisms of stem cells and of  de-differentiating somatic cells. By employing model organisms such as zebrafish and mouse and extending discoveries to human cells and tissues, we hope to gain fundamental insight that can be translated into clinical advances, most notably solving the structural and reconstructive problems of the limbs, face, and head. 

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Mesenchymal tissue regeneration

Websites

Publications: 

Human ARF Specifically Inhibits Epimorphic Regeneration in the Zebrafish Heart.

Genes

Lee S, Hesse R, Tamaki S, Garland C, Pomerantz JH

Functionally heterogeneous human satellite cells identified by single cell RNA sequencing.

eLife

Barruet E, Garcia SM, Striedinger K, Wu J, Lee S, Byrnes L, Wong A, Xuefeng S, Tamaki S, Brack AS, Pomerantz JH

From gut to glutes: The critical role of niche signals in the maintenance and renewal of adult stem cells.

Current opinion in cell biology

Trentesaux C, Striedinger K, Pomerantz JH, Klein OD

TASP1 mutation in a female with craniofacial anomalies, anterior segment dysgenesis, congenital immunodeficiency and macrocytic anemia.

Molecular genetics & genomic medicine

Balkin DM, Poranki M, Forester CM, Dorsey MJ, Slavotinek A, Pomerantz JH

A Cross-sectional Study of the Association between Homelessness and Facial Fractures.

Plastic and reconstructive surgery. Global open

Nguyen AB, Grimes B, Neuhaus J, Pomerantz JH