Ralph Marcucio, PhD

Professor
Department of Orthopaedic Surgery
Primary Thematic Area
Secondary Thematic Area
Research Summary
Craniofacial development, evolutionary biology, trauma, bone repair, angiogenesis
+1 628 206-5366

First, using cutting-edge genomic technology, Dr. Marcucio is examining how the entire genome responds to orthopaedic trauma. This genome-mining approach is aimed at determining the global genome response during fracture repair and allows the possibility to generate improved, highly innovative therapies for people undergoing fracture repair. Second, Ralph is examining the role that the brain plays during normal development of the facial skeleton. Many facial birth defects have an underlying brain malformation, and the goal of the research is to generate novel therapeutic approaches that will allow correcting facial malformations prior to birth.

Publications

Author Correction: MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses.

Scientific data

Devine J, Vidal-García M, Liu W, Neves A, Lo Vercio LD, Green RM, Richbourg HA, Marchini M, Unger CM, Nickle AC, Radford B, Young NM, Gonzalez PN, Schuler RE, Bugacov A, Rolian C, Percival CJ, Williams T, Niswander L, Calof AL, Lander AD, Visel A, Jirik FR, Cheverud JM, Klein OD, Birnbaum RY, Merrill AE, Ackermann RR, Graf D, Hemberger M, Dean W, Forkert ND, Murray SA, Westerberg H, Marcucio RS, Hallgrímsson B

The Developmental Basis for Evolvability.

Evolvability

Benedikt Hallgrímsson, J. David Aponte, Marta Vidal-Garcia, Heather Richbourg, Rebecca Green, Nathan M. Young, James M. Cheverud, Anne L. Calof, Arthur D. Lander, Ralph S. Marcucio

MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses.

Scientific data

Devine J, Vidal-García M, Liu W, Neves A, Lo Vercio LD, Green RM, Richbourg HA, Marchini M, Unger CM, Nickle AC, Radford B, Young NM, Gonzalez PN, Schuler RE, Bugacov A, Rolian C, Percival CJ, Williams T, Niswander L, Calof AL, Lander AD, Visel A, Jirik FR, Cheverud JM, Klein OD, Birnbaum RY, Merrill AE, Ackermann RR, Graf D, Hemberger M, Dean W, Forkert ND, Murray SA, Westerberg H, Marcucio RS, Hallgrímsson B

The Cellular Biology of Fracture Healing.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Bahney CS, Zondervan RL, Allison P, Theologis A, Ashley J, Ahn J, Miclau T, Marcucio R, Hankenson KD

Facial surface morphology predicts variation in internal skeletal shape.

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics

Young NM, Sherathiya K, Gutierrez L, Nguyen E, Bekmezian S, Huang JC, Hallgrímsson B, Lee JS, Marcucio RS

Content Experts.

Larsen's Human Embryology

Richard Anderson, Parker B. Antin, Cammon Arrington, Spencer Beasley, Brian L. Black, Janice L.B. Byrne, Jon Clarke, Martyn Cobourne, Simon J. Conway, Andrew Copp, George P. Daston, Mark Davenport, Jamie Davies, Elaine Dzierzak, Darrell J.R. Evans, John F. Fallon, Richard H. Finnell, Adriana Gittenberger-deGroot, Robert G. Gourdie, Anne Grapin-Botton, Anne Greenough, Barbara F. Hales, Hiroshi Hamada, Christine Hartmann, Takayuki Inagaki, Robyn Jamieson, Chaya Kalcheim, Matthew Kelley, Thomas Knudsen, Catherine E. Krull, Ralph Marcucio, Antoon F. Moorman, Guillermo Olivier, David M. Ornitz, Maurizio Pacifici, Roger K. Patient, Alan O. Perantoni, Theodore Pysher, Maria A. Ros, Yukio Saijoh, Ramesh A. Shivdasani, Jane C. Sowden, Nancy A. Speck, Rajanarayanan Srinivasan, Michael R. Stark, David K. Stevenson, Xin Sun, Cheryll Tickle, Gijs van den Brink, Valerie Wallace, James M. Wells, Arno Wessels, Heather M. Young

The Collaborative Cross, a community resource for the genetic analysis of complex traits.

Nature genetics

Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, Burmeister M, Chesler EJ, Cheverud JM, Clapcote S, Cook MN, Cox RD, Crabbe JC, Crusio WE, Darvasi A, Deschepper CF, Doerge RW, Farber CR, Forejt J, Gaile D, Garlow SJ, Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G, Hayes NL, Heller C, Himmelbauer H, Hitzemann R, Hunter K, Hsu HC, Iraqi FA, Ivandic B, Jacob HJ, Jansen RC, Jepsen KJ, Johnson DK, Johnson TE, Kempermann G, Kendziorski C, Kotb M, Kooy RF, Llamas B, Lammert F, Lassalle JM, Lowenstein PR, Lu L, Lusis A, Manly KF, Marcucio R, Matthews D, Medrano JF, Miller DR, Mittleman G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Morris DG, Mott R, Nadeau JH, Nagase H, Nowakowski RS, O'Hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K, Palmer AA, Pan HJ, Peltonen-Palotie L, Peirce J, Pomp D, Pravenec M, Prows DR, Qi Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC, Seltzer Z, Shimomura K, Shou S, Sillanpää MJ, Siracusa LD, Snoeck HW, Spearow JL, Svenson K, Tarantino LM, Threadgill D, Toth LA, Valdar W, de Villena FP, Warden C, Whatley S, Williams RW, Wiltshire T, Yi N, Zhang D, Zhang M, Zou F