Understanding the basic biology and realizing applicable strategies to enable liver tissue engineering for the treatment of end-stage liver disease.
Mentorship Development:
12/19/19 ACRA: Setting Training Expectations for Trainees on the Academic Career Track (1.5 hours)
2/16/21 Three Truths & Three Tries: Facing & Overcoming Critical Social Justice Challenges at the Micro, Mezzo & Macro Levels
We are interested in mechanisms of oxygen and metabolite sensing in mammals.
Mentorship Development:
4/2020 - Mental Health in a Pandemic: Q&A for Faculty
2/2021 - Three Truths & Three Tries: Facing & Overcoming Critical Social Justice Challenges at the Micro, Mezzo & Macro Levels
7/2021 - Career Conversations
We study the regulation of cell size and shape in fission yeast S. pombe
Mentorship Development:
4/2019 - Acknowledging and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab (Parnassus)
4/2019 - Sharpening your Mentoring Skills (SyMS) with Sharon Milgram (Parnassus)
2/2021 - Three Truths & Three Tries: Facing & Overcoming Critical Social Justice Challenges at the Micro, Mezzo & Macro Levels
4/2023 - Graduate Faculty Development Program: When Someone Isn't Meeting Your Expectations
Our research goal is to develop innovative, mechanism-driven magnetic resonance (MR) metabolic imaging methods for improved detection of neurological disorders and monitoring of therapy response.
Mentorship Development:
12/19/19 ACRA: Setting training expectations for trainees on the academic career track
Dr. Jennifer Y. Chen’s research program focuses on the development of novel antifibrotic therapies and biomarkers for patients with chronic liver disease.
The central theme of the Chorba Lab is to model clinically relevant phenomena in a controlled environment. The major goals are to develop new therapies, targets, and diagnostics that change paradigms in medicine. Inspired by clinical practice, we 1) develop biochemical tools and 2) tackle seemingly undruggable targets to 3) understand the mechanistic basis of cardiometabolic disease and beyond. We work at the interface of chemistry and biology, using the bidirectionality of bench-to-bedside research to expand our findings from any given disease model to the fundamental biology at play.
Mechanisms underlying transcriptional dysregulation, DNA damage responses, inflammation and resistance. Design theranostics targeting the cancer surface proteome and define synthetic lethal interactions.
