Ritchie Chen, PhD, MSc, BS

Asst Professor In Residence

Neurological Surgery

Research Description:

We engineer technologies to study brain-body physiology and to inform new therapeutic approaches for bioelectronic medicine. We fuse approaches in synthetic biology, nanotechnology, device engineering, and systems neuroscience to develop genetically-targeted tools to target, map, readout, and/or control neural circuits while minimizing damage to tissue.

Primary Thematic Area:

Neurobiology

Secondary Thematic Area:

Tissue / Organ Biology & Endocrinology

Research Summary:

Developing technologies to understand and treat nervous system dysfunction. Neural circuits of interoception.

Featured Publications:

Deep brain optogenetics without intracranial surgery.

Nature biotechnology

Chen R, Gore F, Nguyen QA, Ramakrishnan C, Patel S, Kim SH, Raffiee M, Kim YS, Hsueh B, Krook-Magnusson E, Soltesz I, Deisseroth K

Protection of tissue physicochemical properties using polyfunctional crosslinkers.

Nature biotechnology

Park YG, Sohn CH, Chen R, McCue M, Yun DH, Drummond GT, Ku T, Evans NB, Oak HC, Trieu W, Choi H, Jin X, Lilascharoen V, Wang J, Truttmann MC, Qi HW, Ploegh HL, Golub TR, Chen SC, Frosch MP, Kulik HJ, Lim BK, Chung K

Neural Recording and Modulation Technologies.

Nature reviews. Materials

Chen R, Canales A, Anikeeva P

High-Performance Ferrite Nanoparticles through Nonaqueous Redox Phase Tuning.

Nano letters

Chen R, Christiansen MG, Sourakov A, Mohr A, Matsumoto Y, Okada S, Jasanoff A, Anikeeva P

Wireless magnetothermal deep brain stimulation.

Science (New York, N.Y.)

Chen R, Romero G, Christiansen MG, Mohr A, Anikeeva P