Faculty

My lab utilizes genomic and proteomic technologies to study host/pathogen biology in the context of clinical outcomes, develop new diagnostics, and track outbreaks. Key Focus: Pneumonia (including COVID-19), ARDS, sepsis and emerging pathogen surveillance

Our lab specializes in the analysis of highly polymorphic immunogenomic regions in the context of immune function, human health and disease, and evolutionary biology.

Molecular regulation of neural cell fate and circuit assembly

CD8+ T cell immunity to viral pathogens (e.g., HIV, SARS-CoV2) and vaccination at various stages of human development.

My research is focused on uncovering the mechanisms and development of new therapies for the cerebrovascular diseases including brain vascular malformations, stroke, and cognitive dysfunction.

Dr. Jennifer Y. Chen’s research program focuses on the development of novel antifibrotic therapies and biomarkers for patients with chronic liver disease.

Defining conserved mechanisms regulating stem cell behavior and how these are altered with age and in response to chronic or acute changes in metabolism.

Dissecting host mechanisms of tuberculosis (TB) pathogenesis and disease progression, defining immunological correlates of protection, and validating biomarkers and point-of-care diagnostics for TB and COVID-19

Engineering Molecular Technologies for Human Disease