Our research goal is to develop innovative, mechanism-driven magnetic resonance (MR) metabolic imaging methods for improved detection of neurological disorders and monitoring of therapy response.
Mentorship Development:
12/19/19 ACRA: Setting training expectations for trainees on the academic career track
Development of gene therapy, oncolytic virotherapy, and immunotherapy for translational application to cancer (particularly CNS tumors), and genetic engineering strategies for regenerative medicine.
Large-scale analysis of disease genomes by integrating multi-omics data, evolutionary insights, health records, and digitized clinical traits from imaging and wearable sensor readouts.
Understanding the basic biology and realizing applicable strategies to enable liver tissue engineering for the treatment of end-stage liver disease.
Mentorship Development:
12/19/19 ACRA: Setting Training Expectations for Trainees on the Academic Career Track (1.5 hours)
2/16/21 Three Truths & Three Tries: Facing & Overcoming Critical Social Justice Challenges at the Micro, Mezzo & Macro Levels
The Sirota Lab aims to develop computational integrative methods to inform disease diagnostics and therapeutics. Our goal is to integrate different types of omics and clinical data to better understand the role of the immune system in disease.
We strive to understand the events that drive progression of pre-malignant disease into invasive cancer, focusing on gastric and esophageal adenocarcinoma.