
Assistant Professor
Primary Thematic Area
M_PEDS-GASTROENTEROLOGY
Secondary Thematic Area
Research Summary
Our laboratory deciphers the molecular machinery controlling intestinal epithelial renewal and gut signaling via genetic disease models coupled with mouse and human intestinal organoids.
Mentorship Development
12/19/19 ACRA: Setting training expectations for trainees on the academic career track
+1 415 502-2352
As a pediatric gastroenterologist and physician scientist, I am keenly aware of the challenges faced by our pediatric population. The intestinal epithelium comprises the human body’s greatest environmentally exposed surface and is the largest sensory and endocrine organ. My research utilizes human intestinal organoids and animal models to understand how the intestine senses and responds to both regular and inflammatory stimuli. By investigating the molecular pathways involved, we aim to discover new ways to promote intestinal wound healing and modulate the signals contributing to visceral pain syndromes.
Websites
Publications
LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival.
Nature communications
Advances in Enteric Neurobiology: The "Brain" in the Gut in Health and Disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience