James Bayrer, MD, PhD
Assistant Professor
Pediatrics
+1 415 502-2352
Research Description:
As a pediatric gastroenterologist and physician scientist, I am keenly aware of the challenges faced by our pediatric population. The intestinal epithelium comprises the human body’s greatest environmentally exposed surface and is the largest sensory and endocrine organ. My research utilizes human intestinal organoids and animal models to understand how the intestine senses and responds to both regular and inflammatory stimuli. By investigating the molecular pathways involved, we aim to discover new ways to promote intestinal wound healing and modulate the signals contributing to visceral pain syndromes.
Primary Thematic Area:
Developmental & Stem Cell Biology
Secondary Thematic Area:
Tissue / Organ Biology & Endocrinology
Research Summary:
Our laboratory deciphers the molecular machinery controlling intestinal epithelial renewal and gut signaling via genetic disease models coupled with mouse and human intestinal organoids.
Mentorship Development:
12/19/19 ACRA: Setting training expectations for trainees on the academic career track
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Featured Publications: