The Gordan lab combines chemical biology with cancer systems biology strategies to identify new therapeutic targets and drug combinations for GI cancers.
We study host and pathogen mechanisms that regulate growth of Mycobacterium tuberculosis and other mycobacteria. We are using proteomic and genetic tools to probe host responses to infection in macrophages and animal models.
We are designing synthetic receptors and editing the T cell’s genome to better understand T cells function within the tumor microenvironment and ultimately design safe and efficient adoptive T cell therapies