Jonathan Budzik, MD

Assistant Prof. In Residence
Medicine
[email protected]
+1 415 476-7147
Primary Thematic Area: 
Virology & Microbial Pathogenesis
Secondary Thematic Area: 
Immunology
Research Summary: 
We study host and pathogen mechanisms that regulate growth of Mycobacterium tuberculosis and other mycobacteria. We are using proteomic and genetic tools to probe host responses to infection in macrophages and animal models.
Publications: 

History of tuberculosis disease is associated with genetic regulatory variation in Peruvians.

PLoS genetics

Nieto-Caballero VE, Reijneveld JF, Ruvalcaba A, Innocenzi G, Abeydeera N, Asgari S, Lopez K, Iwany SK, Luo Y, Nathan A, Fernandez-Salinas D, Chiñas M, Huang CC, Zhang Z, León SR, Calderon RI, Lecca L, Budzik JM, Murray M, Van Rhijn I, Raychaudhuri S, Moody DB, Suliman S, Gutierrez-Arcelus M

Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection.

PLoS pathogens

Zheng W, Chang IC, Limberis J, Budzik JM, Zha BS, Howard Z, Chen L, Ernst JD

Author Correction: Autophagy restricts Mycobacterium tuberculosis during acute infection in mice.

Nature microbiology

Golovkine GR, Roberts AW, Morrison HM, Rivera-Lugo R, McCall RM, Nilsson H, Garelis NE, Repasy T, Cronce M, Budzik J, Van Dis E, Popov LM, Mitchell G, Zalpuri R, Jorgens D, Cox JS

Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection.

Research square

Zheng W, Chang IC, Limberis J, Budzik J, Zha BS, Howard Z, Chen L, Ernst J

Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during persistent infection.

bioRxiv : the preprint server for biology

Zheng W, Chang IC, Limberis J, Budzik JM, Zha BS, Howard Z, Ernst JD