Hua Su, MD

Professor
Anesthesia
+1 415 353-8683
Research Description: 

I am a Professor in the Department of Anesthesia at the University of California San Francisco. I am an experienced molecular and cellular biologist, has a long-term record in conducting cerebrovascular and cardiovascular research. My laboratory has developed the first brain arteriovenous malformation (bAVM) model in adult mouse that have true AVM lesions in the brain. Founded by the National Institute of Health (NIH) of USA and other Funding agents, my research over the past 19 years focus on studying pathogenesis and developing new therapies for bAVM, ischemic stroke, and cognitive dysfunction. I serve in editorial board of many scientific journals and reviews grants for NIH, American Heart Association, US Department of Defense.

I graduated from Nanjing Medical University in 1982. I undertook a Postdoctoral Research Fellowship at University of California, San Francisco in 1989. I joined the faculty at University of California, San Francisco in 1996 and led a group developing gene and cell-based therapies for cancer, myocardial infarction and ischemic limb diseases. I was recruited to the Center for Cerebrovascular Research in 2008. Since then, my research is focused on identifying disease mechanisms and developing new therapies for cerebrovascular diseases and ischemic stroke. Currently I am the Associate Director for the Center for Cerebrovascular Research and Vice Chair of UCSF Institutional Animal Care and Use Committee.

Primary Thematic Area: 
Vascular & Cardiac Biology
Secondary Thematic Area: 
Neurobiology
Research Summary: 
My research is focused on uncovering the mechanisms and development of new therapies for the cerebrovascular diseases including brain vascular malformations, stroke, and cognitive dysfunction.

Websites

Publications: 

Abstract WP28: Can the reduction of mutant endothelial cells hold promise for treating brain arteriovenous malformation?.

Stroke

Zahra Shabani nabikandi, Leandro Prado, sonali shaligram, Rui Zhang, Wan Zhu, Rich Liang, Alka Yadav, Calvin Wang, Hua Su

Abstract WP34: Targeted delivery of therapeutic genes into brain endothelial cells for treating brain AVMs.

Stroke

Alka Yadav, Rich Liang, kelly press, Annika Schmidt, Zahra Shabani nabikandi, Kun Leng, Calvin Wang, Abinav Sekhar, Joshua Shi, Garth Devlin, Trevor Gonzalez, Aravind Asokan, Hua Su

Updates on the Pathogenesis and Therapeutic Approaches for Hereditary Hemorrhagic Telangiectasia.

Current vascular pharmacology

Yadav A, Shabani Z, Dhaliwal JK, Schmidt A, Su H

Increasing Endoglin Deletion in Endothelial Cells Exacerbates the Severity of Brain Arteriovenous Malformation in Mouse.

Biomedicines

Shabani Z, Do Prado LB, Zhang R, Zhu W, Shaligram SS, Yadav A, Wang C, Su H