Vascular & Cardiac Biology

Opportunities abound for research training in Vascular and Cardiac Biology. UCSF's Cardiovascular Research Institute (CVRI) both provides a home for such research and fosters interactions among investigators throughout UCSF who are interested in cardiovascular biology and disease. The spectrum of investigation ranges from basic structural and chemical biology through cell biology, signaling and invertebrate and vertebrate models of cardiovascular development and disease to human genetics and patient-based disease research. CVRI faculty are represented on all UCSF campuses save Mt. Zion with concentrations on Parnassus and in the new Smith Cardiovascular Research Building at Mission Bay.

 

The Gladstone Institute of Cardiovascular Disease (GICD) is located at Gladstone's new research facility adjacent to UCSF's Mission Bay campus. While independent, Gladstone is formally affiliated with UCSF, and Gladstone investigators hold university appointments and participate in many university activities, including the teaching and training of graduate students. GICD's mission is to contribute to the health and welfare of humankind through research into the causes and prevention of cardiovascular disease.

 

Participating Faculty

Judith Hellman, MD

Primary Thematic Area: 
Immunology
Secondary Thematic Area: 
Vascular & Cardiac Biology
Research Summary: 
Innate Immune Pathways and the Endothelium in Inflammatory Critical Illness

Guo Huang, PhD

Primary Thematic Area: 
Vascular & Cardiac Biology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Comparative study of organ development and regeneration

Lily Jan, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Vascular & Cardiac Biology
Research Summary: 
Potassium Channels

Natalia Jura, PhD

Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
Vascular & Cardiac Biology
Research Summary: 
Molecular basis for Receptor Tyrosine Kinase signaling across the plasma membrane

Jialing Liu, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Vascular & Cardiac Biology
Research Summary: 
Neuroprotection and functional recovery after brain injury

Jacquelyn Maher, MD

Primary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Secondary Thematic Area: 
Vascular & Cardiac Biology
Research Summary: 
Tissue-protective cytokines; fatty liver disease

Takashi Mikawa, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Vascular & Cardiac Biology
Research Summary: 
Developmental Regulation of Organogenesis

Tien Peng, MD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Vascular & Cardiac Biology
Research Summary: 
Contribution of mesenchymal niche to homeostasis, repair, and aging

Robert Raffai, PhD

Primary Thematic Area: 
Vascular & Cardiac Biology
Secondary Thematic Area: 
Immunology
Research Summary: 
Our program explores the impact of metabolic stress on deregulated micro-RNA controlled hematopoiesis and immune cell function in the pathogenesis of atherosclerosis, including through intercellular signaling via exosomes

Sonja Schrepfer, MD, PhD

Primary Thematic Area: 
Vascular & Cardiac Biology
Secondary Thematic Area: 
Immunology
Research Summary: 
We are molecularly modifying pluripotent stem cell lines to create non-immunogenic cells that are protected from post-transplant rejection without affecting the general immune system.

Matthew Springer, PhD

Primary Thematic Area: 
Vascular & Cardiac Biology
Secondary Thematic Area: 
None
Research Summary: 
Angiogenesis & vascular biology, myocardial repair, endothelial function, and second hand smoke

Zena Vexler, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Vascular & Cardiac Biology
Research Summary: 
Brain microenvironment as modulator of neurovascular injury and repair after adult and neonatal stroke

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