Tissue / Organ Biology & Endocrinology

The research of faculty in the areas of Tissue/Organ Biology & Endocrinology addresses biology at the level of the organism, moving from the molecular biology of the individual cell to integrated tissues, organs and organisms, and asking how this biology impacts human disease. UCSF has a long history in the biological sciences that relate to this area of research that is reflected in current Organized Research Units including the Center for Reproductive Sciences, Diabetes Center, Hormone Research Institute, Metabolic Unit, Liver Center, Cardiovascular Research Institute, Lung Biology Center, and Gladstone Institutes.

Among the specific research topics pursued are the genetic basis of obesity, the role of extracellular matrix in regulating cell function, the biological basis of diabetes, reproductive biology, adrenal function, ion fluxes in skin and epithelium, and calcium homeostasis.

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Participating Faculty

Ken Nakamura, MD, PhD

Primary Thematic Area: 
Neurobiology
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
Mitochondrial Pathobiology in Neurodegenerative Disease

Robert Nissenson, PhD

Primary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Signal Transduction Mechanisms in Bone Cell Differentiation and Function

Todd Nystul, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
Epithelial stem cells and cancer

Feroz Papa, MD, PhD

Primary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Protein misfolding diseases and novel therapies

Rushika Perera, PhD

Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
Autophagy: Organelle dynamics and metabolic reprogramming in pancreatic cancer

Paolo Rinaudo, MD, PhD

Primary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Reprogramming of the embryo: Investigating the long term health effects of preimplantation embryo manipulation

Richard Schneider, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
Molecular and Cellular Mechanisms of Craniofacial Development and Evolution

Dean Sheppard, MD

Primary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Secondary Thematic Area: 
Immunology
Research Summary: 
In vivo function of integrins and molecular basis of lung diseases

Jeoung-Sook Shin, PhD

Primary Thematic Area: 
Immunology
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
We are interested in understanding the roles of dendritic cells in health and disease, and the specific mechanisms by which the roles are played.

Julie Sneddon, PhD

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
The niche in pancreatic development and disease

Qizhi Tang, PhD

Primary Thematic Area: 
Immunology
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
Cellular therapies for type 1 diabetes and transplantation

Thea Tlsty, PhD

Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
Regulation of Genomic Instability in Mammalian Cells

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