We use synthetic biology and high-throughput functional genetic screens to understand antigen presentation and T-cell recognition in the context of cancer and other diseases.
Mentorship Development:
10-11/2023 - UCSF Inclusive Mentor/Manager Training
11/2024 - The 4 Touchstones of a High-Functioning Mentoring Relationship
We seek to understand how the organization of the nucleus is established, specialized across cell types, and maintained over time to influence cellular identity.
Mentorship Development:
11/2019 - Equity and Inclusion in the Lab (2 hours)
11/2020 - Optimizing the Efficiency of Your Lab
5/2021 - Sharpening your Mentoring Skills (SyMS)
1/2022 - Equity Based Interview Practices
We study host and pathogen mechanisms that regulate growth of Mycobacterium tuberculosis and other mycobacteria. We are using proteomic and genetic tools to probe host responses to infection in macrophages and animal models.
Our group uses novel gene engineering strategies to decode key genetic programs that we can target to rewire immune cells into effective cancer treatments.
In our lab, we use live imaging in the cochlea to visualize how calcium dysregulation and stress pathways cause hearing loss, to help us identify molecular targets for treatment.
