Esteban G. Burchard, MD, MPH

Department of Bioengineering and Therapeutic Sciences
+1 415 514-9677
Research Description: 

Asthma is the most common chronic disease among children affecting Puerto Rican and African American children more than other races/ethnicities. We study the interplay between genes and the environment to determine the root causes of asthma health disparities in children and adolescents to identify and develop targeted interventions to improve asthma outcomes. The complexities of asthma and respiratory disease require a multi-disciplinary approach. I, therefore, cultivated and maintained over 20 years a network of collaborators with expertise in epidemiology, biostatistics, medicine, molecular and cell biology, and genomics to perform comprehensive research in this area. Together, we are working to ensure that modern advances in genomics will benefit all populations.

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Primary Thematic Area: 
Human Genetics
Secondary Thematic Area: 
Research Summary: 
Pharmacogenomics and Genetic Epidemiology of Pulmonary Diseases



Clotting factor genes are associated with preeclampsia in high-altitude pregnant women in the Peruvian Andes.

American journal of human genetics

Nieves-Colón MA, Badillo Rivera KM, Sandoval K, Villanueva Dávalos V, Enriquez Lencinas LE, Mendoza-Revilla J, Adhikari K, González-Buenfil R, Chen JW, Zhang ET, Sockell A, Ortiz-Tello P, Hurtado GM, Condori Salas R, Cebrecos R, Manzaneda Choque JC, Manzaneda Choque FP, Yábar Pilco GP, Rawls E, Eng C, Huntsman S, Burchard E, Ruiz-Linares A, González-José R, Bedoya G, Rothhammer F, Bortolini MC, Poletti G, Gallo C, Bustamante CD, Baker JC, Gignoux CR, Wojcik GL, Moreno-Estrada A

Methylation risk scores for childhood aeroallergen sensitization: Results from the LISA birth cohort.


Kilanowski A, Chen J, Everson T, Thiering E, Wilson R, Gladish N, Waldenberger M, Zhang H, Celedón JC, Burchard EG, Peters A, Standl M, Hüls A

Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology.

Nature communications

Sajuthi SP, Everman JL, Jackson ND, Saef B, Rios CL, Moore CM, Mak ACY, Eng C, Fairbanks-Mahnke A, Salazar S, Elhawary J, Huntsman S, Medina V, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Zaitlen NA, Oh S, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Rodríguez-Santana J, Burchard EG, Seibold MA

Genetic Ancestry to Improve Precision of Race/ethnicity-based Lung Function Equations in Children.

American journal of respiratory and critical care medicine

Witonsky J, Elhawary JR, Eng C, Rodríguez-Santana J, Borrell LN, Burchard EG

Epigenome-wide association study of lung function in Latino children and youth with asthma.

Clinical epigenetics

Herrera-Luis E, Li A, Mak ACY, Perez-Garcia J, Elhawary JR, Oh SS, Hu D, Eng C, Keys KL, Huntsman S, Beckman KB, Borrell LN, Rodriguez-Santana J, Burchard EG, Pino-Yanes M