Esteban G. Burchard, MD, MPH

Professor
Department of Bioengineering and Therapeutic Sciences
+1 415 514-9677
Research Description: 

Asthma is the most common chronic disease among children affecting Puerto Rican and African American children more than other races/ethnicities. We study the interplay between genes and the environment to determine the root causes of asthma health disparities in children and adolescents to identify and develop targeted interventions to improve asthma outcomes. The complexities of asthma and respiratory disease require a multi-disciplinary approach. I, therefore, cultivated and maintained over 20 years a network of collaborators with expertise in epidemiology, biostatistics, medicine, molecular and cell biology, and genomics to perform comprehensive research in this area. Together, we are working to ensure that modern advances in genomics will benefit all populations.

Visit my lab page to learn more: https://pharm.ucsf.edu/burchard

Primary Thematic Area: 
Human Genetics
Secondary Thematic Area: 
None
Research Summary: 
Pharmacogenomics and Genetic Epidemiology of Pulmonary Diseases

Websites

Publications: 

Multiomics Analysis Identifies BIRC3 as a Novel Glucocorticoid Response-Associated Gene.

The Journal of allergy and clinical immunology

Kan M, Diwadkar AR, Shuai H, Joo J, Wang AL, Ong MS, Sordillo JE, Iribarren C, Lu MX, Hernandez-Pacheco N, Perez-Garcia J, Gorenjak M, Potocnik U, Burchard EG, Pino-Yanes M, Wu AC, Himes BE

Disentangling the impact of alcohol use and hepatitis C on insulin action in Latino individuals.

Alcoholism, clinical and experimental research

Kim RG, Kramer-Feldman J, Bacchetti P, Grimes B, Burchard E, Eng C, Hu D, Hellerstein M, Khalili M

Pharmacogenetic studies of long-acting beta agonist and inhaled corticosteroid responsiveness in randomised controlled trials of individuals of African descent with asthma.

The Lancet. Child & adolescent health

Ortega VE, Daya M, Szefler SJ, Bleecker ER, Chinchilli VM, Phipatanakul W, Mauger D, Martinez FD, Herrera-Luis E, Pino-Yanes M, Hawkins GA, Ampleford EJ, Kunselman SJ, Cox C, Bacharier LB, Cabana MD, Cardet JC, Castro M, Denlinger LC, Eng C, Fitzpatrick AM, Holguin F, Hu D, Jackson DJ, Jarjour N, Kraft M, Krishnan JA, Lazarus SC, Lemanske RF, Lima JJ, Lugogo N, Mak A, Moore WC, Naureckas ET, Peters SP, Pongracic JA, Sajuthi SP, Seibold MA, Smith LJ, Solway J, Sorkness CA, Wenzel S, White SR, Burchard EG, Barnes K, Meyers DA, Israel E, Wechsler ME, NHLBI AsthmaNet

Role of Sex on the Genetic Susceptibility to Childhood Asthma in Latinos and African Americans.

Journal of personalized medicine

Espuela-Ortiz A, Herrera-Luis E, Lorenzo-Díaz F, Hu D, Eng C, Villar J, Rodriguez-Santana JR, Burchard EG, Pino-Yanes M

Lymph node-resident dendritic cells drive TH2 cell development involving MARCH1.

Science immunology

Castellanos CA, Ren X, Gonzalez SL, Li HK, Schroeder AW, Liang HE, Laidlaw BJ, Hu D, Mak ACY, Eng C, Rodríguez-Santana JR, LeNoir M, Yan Q, Celedón JC, Burchard EG, Zamvil SS, Ishido S, Locksley RM, Cyster JG, Huang X, Shin JS