Esteban G. Burchard, MD, MPH

Professor
Department of Bioengineering and Therapeutic Sciences
[email protected]
+1 415 514-9677
Research Description: 

Asthma is the most common chronic disease among children affecting Puerto Rican and African American children more than other races/ethnicities. We study the interplay between genes and the environment to determine the root causes of asthma health disparities in children and adolescents to identify and develop targeted interventions to improve asthma outcomes. The complexities of asthma and respiratory disease require a multi-disciplinary approach. I, therefore, cultivated and maintained over 20 years a network of collaborators with expertise in epidemiology, biostatistics, medicine, molecular and cell biology, and genomics to perform comprehensive research in this area. Together, we are working to ensure that modern advances in genomics will benefit all populations.

Visit my lab page to learn more: https://pharm.ucsf.edu/burchard

Primary Thematic Area: 
Human Genetics
Secondary Thematic Area: 
None
Research Summary: 
Pharmacogenomics and Genetic Epidemiology of Pulmonary Diseases

Websites

Publications: 

Robust, flexible, and scalable tests for Hardy-Weinberg Equilibrium across diverse ancestries.

Genetics

Kwong AM, Blackwell TW, LeFaive J, de Andrade M, Barnard J, Barnes KC, Blangero J, Boerwinkle E, Burchard EG, Cade BE, Chasman DI, Chen H, Conomos MP, Cupples LA, Ellinor PT, Eng C, Gao Y, Guo X, Ryan Irvin M, Kelly TN, Kim W, Kooperberg C, Lubitz SA, Mak ACY, Manichaikul AW, Mathias RA, Montasser ME, Montgomery CG, Musani S, Palmer ND, Peloso GM, Qiao D, Reiner AP, Roden DM, Shoemaker MB, Smith JA, Smith NL, Lasky Su J, Tiwari HK, Weeks DE, Weiss ST, NHLBI Trans-Omics for Precision Medicine
(TOPMed) Consortium, TOPMed Analysis Working Group , Scott LJ, Smith AV, Abecasis GR, Boehnke M, Min Kang H

Genome-wide association studies of exacerbations in children using long-acting beta2-agonists.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

Mapping the 17q12-21.1 Locus for Variants Associated with Early-onset Asthma in African Americans.

American journal of respiratory and critical care medicine

Gui H, Levin AM, Hu D, Sleiman P, Xiao S, Mak AC, Yang M, Barczak AJ, Huntsman S, Eng C, Hochstadt S, Zhang E, Whitehouse K, Simons S, Cabral W, Takriti S, Abecasis G, Blackwell TW, Kang HM, Nickerson DA, Germer S, Lanfear DE, Gilliland F, Gauderman WJ, Kumar R, Erle DJ, Martinez FD, Hakonarson H, Burchard EG, Williams LK