BMS Journal Club 2015-16

2015-16 Schedule

September 3, 2015-June 2, 2016

Journal Club Chairs: Mike German, MD and Suzanne Noble, MD, PhD
Day/Time: Thursdays, 12:00-1:00 p.m. except as noted
Location: N-225, Parnassus & videoconferenced to Room MH-1405, Mission Bay.
Live stream & archive: Spring 2016Winter 2016Fall 2015, Summer 2015 (9/3) (UCSF MyAccess login required)


September 3, 2015
Mission Bay videoconference: MH-1405
Adair Borges (student)
“Inducing MDT before it was cool: Hip(ster)BA - promoter structures reveal the basis of heritable multidrug tolerance”
Schumacher MA et al. HipBA-promoter structures reveal the basis of heritable multidrug tolerance. Nature. 2015 Aug 6;524(7563):59-64. doi: 10.1038/nature14662.
Coaches: Joseph Bondy-Denomy and Jeffrey Cox

Oren Rosenberg (faculty)
"Hybrid Approaches to Understand Complex, Macromolecular Machines"
Durand E et al. Biogenesis and structure of a type VI secretion membrane core complex. Nature. 2015 Jul 22;523(7562):555–60.

September 10, 2015
Mission Bay videoconference: MH-1405
Eric Wigton (student)
"Micey's Mom Has Got it Going on:  Maternal Microchimerism Enforces Cross Generational Reproductive Fitness."
Kinder JM et al. Cross-Generational Reproductive Fitness Enforced by Microchimeric Maternal Cells. Cell. 2015 July 30; 162 (3) 505–515. doi:10.1016/j.cell.2015.07.006
Coaches: Trevor Burt and Mark Ansel

Jason Cyster (faculty)
"VISTA of death: p53-induced gene promotes apoptotic cell clearance."
Yoon KW et al. Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53. Science. 2015 July 31:349 (6247) doi: 10.1126/science.1261669.

September 17, 2015
Mission Bay videoconference: MH-1405
Corey Tan (student)
"Use the (replication) forks: T cell help controls cell cycle speed in germinal center B cells."
Gitlin A et al. T cell help controls the speed of the cell cycle in germinal center B cells. Science. 2015 Aug 7;349(6248):643-646.
Coaches: Julie Zikherman and Jason Cyster

Julie Sneddon (faculty)
“It’s Just a Flesh Wound: Identification and Isolation of a Dermal Lineage with Intrinsic Fibrogenic Potential.”
Rinkevich Y, et al. Skin fibrosis. Identification and isolation of a dermal lineage with intrinsic fibrogenic potential. Science. 2015; Apr 17;348(6232):aaa2151. doi: 10.1126/science.aaa2151.

September 24, 2015
Mission Bay videoconference: MH-1405
Luke Smith (student)
"Survival of the fittest: how competition for cadherin/catenin complexes determines dendritic spine fate."
Bian WJ, et al. Coordinated spine pruning and maturation mediated by inter-spine competition for cadherin/catenin complexes. Cell. 2015; 162, 808-822.
Coaches: Saul Villeda and Erik Ullian

Diana Laird (faculty)
"Why wait? Start defying your parents even before (their) birth!"
Tang WW, et al. A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development. Cell. 2015 Jun 4;161(6):1453-67. doi: 10.1016/j.cell.2015.04.053.

October 1, 2015
Mission Bay videoconference: MH-1405
Elze Rackaityte (student)
"That’s so random! Stochastic pathogen cell-to-cell variability drives heterogeneity in host immune responses."
Avraham R, et al. Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses. Cell. 2015 Sep 2. pii: S0092-8674(15)01041-7. doi: 10.1016/j.cell.2015.08.027.
Coaches: Oren Rosenberg and Joseph Bondy-Denomy

Andrew Brack (faculty)
"Stem cell quiescence and injury sensing."
Rodgers JT, et al. mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert). Nature. 2014 Jun 19;510(7505):393-6. doi: 10.1038/nature13255.

October 8, 2015
Mission Bay videoconference: MH-1405
Andrew Mancini (student)
"Dumpster diving for dCTPs: CDA-directed metabolism of epigenetic nucleosides in cancer."
Zauri M, et al. CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer. Nature. 2015 Aug 6. 524(7563):114-8. doi: 10.1038/nature14948.
Coaches: Andrei Goga and Aaron Tward

Jorge Ortiz-Carpena (student)
"Craigslist Buddies for mRNAs: Spatiotemporal dynamics of inflammatory mRNA regulation mediated by Regnase-1 and Roquin."
Mino T, et al. Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms. Cell. 2015; 161, 1058-1073. dx.doi.org/10.1016/j.cell.2015.04.029.
Coaches: Mark Ansel and Clifford Lowell

October 15, 2015
Mission Bay videoconference: MH-1405
Erick Lu (student)
"A trail of breadcrumbs: Neutrophil-derived cellular fragments promote CD8+ T cell migration during influenza."
Lim K, et al. Neutrophil trails guide influenza-specific CD8+ T cells in the airways. Science. 2015 Sep 4; 349 (6252) doi: 10.1126/science.aaa4352.
Coaches: Jason Cyster and Shaeri Mukherjee

Saul Villeda (faculty)
"There’s something fishy about aging."
Harel I, et al. A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate. Cell. 2015 Feb 26;160(5):1013-26. doi: 10.1016/j.cell.2015.01.038.

October 22, 2015
Mission Bay videoconference: MH-1405
Abby Kindberg (student)
"A Tense Situation: The Role of Cortical Tension in Early Embryo Development."
Samarage CR, et al. Cortical Tension Allocates the First Inner Cells of the Mammalian Embryo.Dev Cell. 2015 Aug 24;34(4):435-47. doi: 10.1016/j.devcel.2015.07.004.
Coaches: Jeff Bush and Susan Fisher

JJ Miranda (faculty)
"Don’t turn around, ‘cause you’re gonna see my heart breaking."
Guo Y, et al. CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function. Cell. 2015 Aug 13;162(4):900-10. doi: 10.1016/j.cell.2015.07.038.

October 29, 2015
Mission Bay videoconference: MH-1405
Natanya Kerper (student)
Title TBD
Zhu X, et al. Microtubules Negatively Regulate Insulin Secretion in Pancreatic β Cells. Dev Cell.2015 Sep 28;34(6):656-68. doi: 10.1016/j.devcel.2015.08.020.
Coaches: Matthias Hebrok and Torsten Wittman

Melanie Ott (faculty)
"SECcessful viral culture: SEC14L2 enables pan-genotype HCV replication in cell culture."
Saeed M, et al. SEC14L2 enables pan-genotype HCV replication in cell culture. Nature. 2015 Aug 27;524(7566):471-5. doi: 10.1038/nature14899.

November 5, 2015
Mission Bay videoconference: MH-1405
Ariel Kauss (student)
"What's in a Niche? Two models of hepatic regeneration."
Font-Burgada, et al. Hybrid Periportal Hepatocytes Regenerate to the Injured Liver without Giving Rise to Cancer. Cell. 2015 Aug 13;162(4):766-79. doi: 10.1016/j.cell.2015.07.026. 
and
Wang B, et al. Self Renewing diploid Axin2+ cells fuel homeostatic renewal of the liver. Nature.2015 Aug 13;524(7564):180-5. doi: 10.1038/nature14863.
Coaches: Todd McDevitt and Holger Willenbring

Rosemary Akhurst (faculty)
"Tumor Neoantigens in Immunotherapy: Quality or Quantity?"
Van Allen E, et al. Genomic correlates of response to CTLA-4 blockade in metastatic melanoma. Science. 2015 Oct 9;350(6257):207-11. doi: 10.1126/science.aad0095.

November 12, 2015
Mission Bay videoconference: MH-1405
Emily Jones (student)
"Fingerprint Your Brain: How a Few MRIs Might Identify You and Predict Your Intelligence."
Finn ES, et al. Functional connectome fingerprinting: identifying individuals using patterns of brain connectivity. Nat Neurosci. 2015 Nov;18(11):1664-71. doi: 10.1038/nn.4135.
Coaches: Yadong Huang and Aimee Kao

Ethan Weiss (faculty)
"What does GH stand for? A new twist on an old and important UCSF story."
Brooks AJ, et al. Mechanism of Activation of Protein Kinase JAK2 by the Growth Hormone Receptor. Science. 2014 May 16;344(6185):1249783. doi: 10.1126/science.1249783.

November 19, 2015
Mission Bay videoconference: MH-1405
Bernadette Hsu (student)
"3D organoids: A new way to personalize pancreatic cancer."
Huang L, et al. Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids. Nat Med. 2015 Oct 26. doi: 10.1038/nm.3973.
Coaches: Holger Willenbring and Rushika Perera

Pamela Munster (faculty)
"More news with Immunotherapy."
Le DT, et al. PD-1 Blockade in Tumors with Mismatch-Repair Deficiency. N Engl J Med. 2015 Jun 25;372(26):2509-20. doi: 10.1056/NEJMoa1500596.

December 3, 2015
Mission Bay videoconference: MH-1405
Dror Assa (student)
"Taking the STING out."
Wu Jj, et al. Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein. Cell Host Microbe. 2015 Sep 9;18(3):333-44. doi: 10.1016/j.chom.2015.07.015. Epub 2015 Aug 27.
Coaches: Anita Sil and Anthony DeFranco

Lily Jan (faculty)
"A refreshingly new potassium channel."
Cang C, et al. TMEM175 Is an Organelle K(+) Channel Regulating Lysosomal Function. Cell. 2015 Aug 27;162(5):1101-12. doi: 10.1016/j.cell.2015.08.002.

January 7, 2016
Mission Bay videoconference: MH-1405
Qi Yan Ang (student)
"Bacteria come into focus: New tool for imaging gut microbiota spatial organization."
Earle KA, et al. Quantitative Imaging of Gut Microbiota Spatial Organization. Cell Host Microbe.2015 Oct 14;18(4):478-88. doi: 10.1016/j.chom.2015.09.002.
Coaches: Kurt Thorn and Peter Turnbaugh

Ying-Hui Fu (faculty)
"How much time can a cup of coffee get for you?"
Burke TM, et al. Effects of caffeine on the human circadian clock in vivo and in vitro. Sci Transl Med. 2015 Sep 16;7(305):305ra146. doi: 10.1126/scitranslmed.aac5125.

January 14, 2016
Mission Bay videoconference: MH-1405
Sophia Levan (student)
"Which one's the chicken? Interrupting the Host-Microbe Interface."
Levy, M. et al. Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling. Cell 163, 1428–1443 (2015).
Coaches: Suzanne Noble and Tony DeFranco

Peter Turnbaugh (faculty)
"Where does your microbiome go when you die?"
Metcalf JL, et al. Microbial community assembly and metabolic function during mammalian corpse decomposition. Online December 10 2015, Science  DOI: 10.1126/science.aad2646.

January 21, 2016
*Special Time - 5:00 pm.*
** There will be no videoconference to Mission Bay for this session. **
Francesca Aloisio (student)
"Capping Optional Beyond This Point: 5' UTR m6A promotes cap-independent translation."
Meyer, K. et al. 5' UTR m6A Promotes Cap-Independent Translation. Cell 163, 999-1010 (2015).
Coaches: Michael McManus and Davide Ruggero

Akiko Hata (faculty)
"Fibrodysplasia Ossificans Progressive (FOP)—the disease of mismatched relationship."
Hatsell SJ, et al. ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A. Sci Transl Med. 2015 Sep 2;7(303):303ra137. doi: 10.1126/scitranslmed.aac4358.

January 28, 2016
Mission Bay videoconference: MH-1405
Jennifer Liu (student)
"Autophagy-mediated degradation of nuclear lamina: a new role for self-eating."
Dou Z, et al. Autophagy mediates degradation of nuclear lamina. Nature. 2015 Nov 5;527(7576):105-9. doi: 10.1038/nature15548.
Coaches: Jay Debnath and Rushika Perera

February 4, 2016
Mission Bay videoconference: MH-1405
Trisha Macrae (student)
"Rethinking Meatless Mondays: a low-protein paternal diet affects small RNA levels in maturing sperm."
Sharma U, et al. Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals. Science. Online 2015 Dec 31. doi: 10.1126/science.aad6780.
Coaches: Miguel Ramalho-Santos and Diana Laird

Scott Kogan (faculty)
“Yet another link between proteostasis and (hematologic) neoplasia!”
Osorio FG, et al. Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling. Nat Med. 2016 Jan;22(1):91-6. doi: 10.1038/nm.4013.

February 11, 2016
*Special Time - 5:00 pm.*
** There will be no videoconference to Mission Bay for this session. **
John Gagnon (student)
Lamarckian Inheritance of Acquired Traits: Back in Vogue?
Chen Q, et al. Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder. Science. 2016 Jan 22;351(6271):397-400. doi: 10.1126/science.aad7977.
Coaches: Rob Judson and Mark Ansel

Michael Rosenblum (faculty)
"Regulatory T cells - to be suppressive or not? That is the question."
Arpaia N, et al. A Distinct Function of Regulatory T Cells in Tissue Protection. Cell. 2015 Aug 27;162(5):1078-89. doi: 10.1016/j.cell.2015.08.021.

February 18, 2016
Mission Bay videoconference: MH-1405
Walter Mancia (student)
"A Western-Lifestyle: FMD diets, the secret to longevity."
Brandhorst S, et al. A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan. Cell Metab. 2015 Jul 7;22(1):86-99. doi: 10.1016/j.cmet.2015.05.012.
Coaches: Saul Villeda and Yin Shen

February 25, 2016
Mission Bay videoconference: MH-1405
Andrew McKinney (student)
"Astrocytes PTENiate brain metastasis."
Zhang L, et al. Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth. Nature. 2015 Nov 5;527(7576):100-4. doi: 10.1038/nature15376.
Coaches: Michael McManus and Aaron Tward

March 3, 2016
Mission Bay videoconference: MH-1405
Andrew McNeal (student)
"A Perfect Day for Melanomafish?"
Kaufman C, et al. A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation. Science. 2016 Jan 29;351(6272):aad2197. doi: 10.1126/science.aad2197.
Coaches: Aaron Tward and Rob Judson

Diane Barber (faculty)
"Follow the glucose trail to find where to go."
Dupuy F, et al. PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer. Cell Metabolism (2015) 22:577–589.

March 10, 2016
Mission Bay videoconference: MH-1405
Lauren Meyer (student)
"Phthalimide conjugation: dBETter choice."
Winter GE, et al. Phthalimide conjugation as a strategy for in vivo target protein degradation.Science. 2015 Jun 19;348(6241):1376-81. doi: 10.1126/science.aab1433.
Coaches: Kevin Shannon and Ben Braun

March 17, 2016
Mission Bay videoconference: MH-1405
Michelle Mintz (student)
"Germinal Centers at the End of the Brainbow."
Tas JMJ, et al. Visualizing antibody affinity maturation in germinal centers. Science 1–11 (2016). doi:10.1126/science.aad3439.
Coaches: Jason Cyster and Chris Allen

Sarah McMahon (student)
"Do these genes make me look fat?"
Claussnitzer M, et al. FTO Obesity Variant Circuitry and Adipocyte Browning in Humans. N Engl J Med. 2015 Sep 3;373(10):895-907. doi: 10.1056/NEJMoa1502214.
Coaches: Saptarsi Haldar and Shingo Kajimura

March 24, 2016
Mission Bay videoconference: MH-1405
Tonatiuh Montoya (student)
"All quiescent on the stem cell front."
Zismanov V, et al. Phosphorylation of eIF2α Is a Translational Control Mechanism Regulating Muscle Stem Cell Quiescence and Self-Renewal. Cell Stem Cell. 18 (1): 79-90. doi: 10.1016/j.stem.2015.09.020.
Coaches: Andrew Brack and Davide Ruggero

Casey Beppler (student)
"Mooch no more: a 3 punch knockout to intracellular parasites."
Dotiwala F, et al. Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites. Nat Med. 2016 Feb;22(2):210-6. doi: 10.1038/nm.4023.
Coaches: Jeroen Roose and Lewis Lanier

March 31, 2016
Mission Bay videoconference: MH-1405
Phi Nguyen (student)
"Turning back the clock: a role for senescent cells in healthspan."
Baker, D. J. et al. Naturally occurring p16Ink4a-positive cells shorten healthy lifespan. Nature.2016 Feb 11;530(7589):184-9. doi: 10.1038/nature16932.
Coaches: Saul Villeda and Anna Molofsky

Daniel Bunis (student)
"Heads or Tails: Bias in the antibody response to Influenza."
Andrews SF, et al. Immune history profoundly affects broadly protective B cell responses to influenza. Sci Transl Med. 2015 Dec 2;7(316):316ra192. doi: 10.1126/scitranslmed.aad0522.
Coaches: Jason Cyster and Tony DeFranco

April 7, 2016
**Please note room change: N-217**
Mission Bay videoconference: MH-1405
Ariane Panzer (student)
"Mama Said There'd Be Microbes Like This."
Gomez de Aguero, M. et al. The maternal microbiota drives early postnatal innate immune development. Science. 2016 Mar 18;351(6279):1296-302. doi:10.1126/science.aad2571. 
Coaches: Susan Lynch and Suzanne Noble

Carlos Castellanos (student)
"T cells never forget."
Tubo NJ, et al. Most microbe-specific naïve CD4+ T cells become memory cells during infection.Science. 2016 Jan 29;351(6272):511-4. doi: 10.1126/science.aad0483.
Coaches: Michael Rosenblum and Mark Ansel

April 14, 2016
Mission Bay videoconference: MH-1405
Mark-Phillip Pebworth (student)
"Batten down the hatches!"
Miner JJ, et al. The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-barrier integrity. Nat Med. 2015 Dec;21(12):1464-72. doi: 10.1038/nm.3974. Epub 2015 Nov 2
Coaches: Arnold Kriegstein and Charles Chiu

Jessica Cortez (student)
"A Tale of Two Peptides: A new class of hybrid autoantigens trigger Type 1 Diabetes."
Delong T, et al. Pathogenic CD4 T Cells in Type 1 Diabetes Recognize Epitopes Formed by Peptide Fusion. Science. 2016 Feb 12;351(6274):711-4. doi: 10.1126/science.aad2791.
Coaches: Jeff Bluestone and Qizhi Tang

April 21, 2016
Mission Bay videoconference: MH-1405
Hanna Retallack (student)
"Depending on miRNA for livelihood: a livestock virus tale"
Scheel TK, et al. A Broad RNA Virus Survey Reveals Both miRNA Dependence and Functional Sequestration. Cell Host Microbe. 2016 Mar 9;19(3):409-23. doi: 10.1016/j.chom.2016.02.007
Coaches: Melanie Ott and Joe Bondy-Denomy

Germaine Yong (student)
"You Are What You Eat?"
Blanton LV, et al. Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children. Science. 2016 Feb 19;351(6275). Pii: aad3311. doi: 10.1126/science.aad3311.
Coaches: Susan Lynch and Peter Turnbaugh

April 28, 2016
**Please note room change: N-217**
Mission Bay videoconference: MH-1405
Tina Solvik (student)
"Imitation is the sincerest form of flattery: a host-produced autoinducer-2 mimic activates bacterial quorum sensing."
Ismail AS, et al. A host-produced autoinducer-2 mimic activates bacterial quorum sensing. Cell Host Microbe. 2016 Apr 13;19(4):470-480. doi: 10.1016/j.chom.2016.02.020. Epub 2016 Mar 17.
Coaches: Joe Bondy-Denomy and Suzanne Noble

Andrea Eastes (student)
"Beta Call p16-Ink4a"
Helman A, et al. p16Ink4a-induced senescence of pancreatic beta cells enhances insulin secretion.Nat Med. 2016 Apr;22(4):412-20. doi: 10.1038/nm.4054. Epub 2016 Mar 7.
Coaches: Julie Sneddon and Andrew Brack

May 5, 2016
Mission Bay videoconference: MH-1405
Tina Tianjiao Su (student)
"Finding your s(Ig)nificant other: making synaptic connections in the Drosophila medulla" 
Tan L, et al. Ig Superfamily Ligand and Receptor Pairs Expressed in Synaptic Partners in Drosophila. Cell. 2015 Dec 17;163(7):1756-69. doi:10.1016/j.cell.2015.11.021.
Coaches: Yuh Nung Jan and Lily Jan

Kimberly Hoi (student)
"Scar Wars: A New Hope" 
Anderson MA, et al. Astrocyte scar formation aids central nervous system axon regeneration.Nature. 2016 Mar 30. doi: 10.1038/nature17623.
Coaches: Anna Molofsky and Erik Ullian

May 12, 2016
Mission Bay videoconference: MH-1405
Rebecca Jaszczak (student)
"Breaking and Entering: ESCRT covers the damage"
Raab M, et al. ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death. Science. 2016 Apr 15;352(6283):359-362. doi:10.1126/science.aad7611. Epub 2016 Mar 24.
Coaches: Jeff Bush and Licia Selleri

Alana Horowitz (student)
"Death-Defying Experiments: Balancing NAD+ levels with a nutritional supplement increases stem cell function with age" 
Zhang H, et al. NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice. Science. 10.1126/science.aaf2693 (2016).
Coaches: Andrew Brack and Saul Villeda

May 19, 2016

Mission Bay videoconference: MH-1405
Emily Davis (student)
"Xist is SeXist" 
Gayen S, et al. Sex-specific silencing of X-linked genes by Xist RNA. Proc Natl Acad Sci U S A.2016 Jan 19;113(3):E309-18. doi: 10.1073/pnas.1515971113. Epub 2016 Jan 6.
Coaches: Dena Dubal and Barbara Panning

Sasha Targ (student)
"TBD" 
Tehranchi AK, et al. Pooled ChIP-Seq Links Variation in Transcription Factor Binding to Complex Disease Risk. Cell. 2016 Apr 21;165(3):730-41. doi: 10.1016/j.cell.2016.03.041. Epub 2016 Apr 14.
Coaches: Jimmie Ye and Yin Shen

May 26, 2016
Mission Bay videoconference: MH-1405

Daniel Wong (student)
"Beta cells to glycemic control: we have a polymer. Over." 
Vegas AJ, et al. Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice. Nat Med. 2016 Mar;22(3):306-11. doi: 10.1038/nm.4030. Epub 2016 Jan 25.
Coaches: Julie Sneddon and Qizhi Tang

Ruiji Jiang (student)
"The SCNT of a Neuron: Using cloning to reveal the mutational spectrum of MT olfactory bulb neurons." 
Hazen JL, et al. The Complete Genome Sequences, unique mutational spectra, and developmental potency of adult neurons revealed by cloning. Neuron. 2016 Mar 16;89(6):1223-36. doi: 10.1016/j.neuron.2016.02.004. Epub 2016 Mar 3.
Coaches: Aimee Kao and Elliott Sherr

June 2, 2016
Mission Bay videoconference: MH-1405
Simone Kurial (student)
"There Will Be Blood: The role of vasculature in the bone marrow nice" 
Itkin T, et al. Distinct bone marrow blood vessels differentially regulate haematopoiesis.Nature. 2016 Apr 21;532(7599):323-8. doi: 10.1038/nature17624. Epub 2016 Apr 13.
Coaches: Matt Springer and Jeff Bush

Tina Zheng (student)
"For the WNT: Breaking down the Blood Brain Barrier" 
Phoenix TN, et al. Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype. Cancer Cell. 2016 Apr 11;29(4):508-22. doi: 10.1016/j.ccell.2016.03.002. Epub 2016 Mar 31.
Coaches: Theodore Nicolaides, Kyle Walsh, and William Weiss