Proceedings of the National Academy of Sciences of the United States of America

Tissue-restricted inhibition of mTOR using chemical genetics.

Proceedings of the National Academy of Sciences of the United States of America

Wassarman DR, Bankapalli K, Pallanck LJ, Shokat KM

A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters.

Proceedings of the National Academy of Sciences of the United States of America

Chaturvedi S, Beutler N, Vasen G, Pablo M, Chen X, Calia G, Buie L, Rodick R, Smith D, Rogers T, Weinberger LS

Miat and interacting protein Metadherin maintain a stem-like niche to promote medulloblastoma tumorigenesis and treatment resistance.

Proceedings of the National Academy of Sciences of the United States of America

Peng KL, Vasudevan HN, Lockney DT, Baum R, Hendrickson RC, Raleigh DR, Schmitt AM

A photo-switchable assay system for dendrite degeneration and repair in Drosophila melanogaster.

Proceedings of the National Academy of Sciences of the United States of America

Liu HH, Hsu CH, Jan LY, Jan YN

T cells use distinct topographical and membrane receptor scanning strategies that individually coalesce during receptor recognition.

Proceedings of the National Academy of Sciences of the United States of America

Cai E, Beppler C, Eichorst J, Marchuk K, Eastman SW, Krummel MF

An excitatory peri-tegmental reticular nucleus circuit for wake maintenance.

Proceedings of the National Academy of Sciences of the United States of America

Webb JM, Ma M, Yin C, Ptácek LJ, Fu YH

Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles.

Proceedings of the National Academy of Sciences of the United States of America

Syed AM, Ciling A, Taha TY, Chen IP, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Suryawanshi R, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Spraggon L, Tabata T, Ott M, Doudna JA

Genetic variation that determines TAPBP expression levels associates with the course of malaria in an HLA allotype-dependent manner.

Proceedings of the National Academy of Sciences of the United States of America

Walker-Sperling V, Digitale JC, Viard M, Martin MP, Bashirova A, Yuki Y, Ramsuran V, Kulkarni S, Naranbhai V, Li H, Anderson SK, Yum L, Clifford R, Kibuuka H, Ake J, Thomas R, Rowland-Jones S, Rek J, Arinaitwe E, Kamya M, Rodriguez-Barraquer I, Feeney ME, Carrington M

Tropism of SARS-CoV-2 for human cortical astrocytes.

Proceedings of the National Academy of Sciences of the United States of America

Andrews MG, Mukhtar T, Eze UC, Simoneau CR, Ross J, Parikshak N, Wang S, Zhou L, Koontz M, Velmeshev D, Siebert CV, Gemenes KM, Tabata T, Perez Y, Wang L, Mostajo-Radji MA, de Majo M, Donohue KC, Shin D, Salma J, Pollen AA, Nowakowski TJ, Ullian E, Kumar GR, Winkler EA, Crouch EE, Ott M, Kriegstein AR

GPR174 signals via Gαs to control a CD86-containing gene expression program in B cells.

Proceedings of the National Academy of Sciences of the United States of America

Wolf EW, Howard ZP, Duan L, Tam H, Xu Y, Cyster JG

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