We study how genetic changes that accumulated over the last 6 million years of human evolution influence specialized features of brain development using single cell genomics, cerebral organoid models of ape brain development, and genome engineering.
Early stages of development of neurodegenerative diseases in humans. Dr. Grinberg employs a combination of well characterized postmortem human brain tissue, Neurons derived from IPSc lines and advanced methods of imaging processing.
We study how the different cell types in the liver, in particular the hepatocyte, are generated during development, patterned and maintained during adulthood, and regenerate after injury.
Genomic instability and DNA repair in neural cells
Mentorship Development:
4/11/19 Acknowleding and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab (Mission Bay)
12/19/19 ACRA: Setting Training Expectations for Trainees on the Academic Career Track (1.5 hours)
3/10/20 Promoting Student Mental Health:A Presentation and Discussion (Staff and Faculty)
4/30/20 Mental Health in a Pandemic: Q&A for Faculty
10/20/20 Gathering in Community: a Training for Faculty and Staff
Our lab applies single-cell analysis approaches on in vitro and clinical specimens to study the interplay between immune cells & viral pathogens including HIV & SARS-CoV-2, & to study the properties of immune cells in mucosal tissues in health & disease
The Gilbert lab's expertise is in synthetic biology, functional genomics and cancer biology.
Mentorship Development:
4/26/19 Sharpening your Mentoring Skills (SyMS) with Sharon Milgram (Mission Bay)
12/12/19 ACRA: Setting Training Expectations for Trainees on the Academic Career Track (1.5 hours)
4/23/20 Effective Strategies for IDPs
10/20/20 Gathering in Community: a Training for Faculty and Staff
Regulation of hepatic development, metabolism, and paths towards cancer.
Mentorship Development:
4/12/19 Acknowleding and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab (Parnassus)
12/12/19 ACRA: Setting Training Expectations for Trainees on the Academic Career Track (1.5 hours)
10/20/20 Gathering in Community: a Training for Faculty and Staff
Our lab focuses on developing computational and experimental strategies to reveal and mechanistically characterize novel regulatory pathways that drive cancer metastasis.
Mentorship Development:
4/11/19 Acknowleding and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab (Mission Bay)
10/20/20 Gathering in Community: a Training for Faculty and Staff
Immunmodulatory, cytoreductive chemotherapeutic and stem cell transplantation approaches to HIV-1 cure. Design and implementation of novel nano/microtechnologies to characterize viral reservoirs.
