The Journal of clinical investigation

Cancer-associated mesothelial cells promote ovarian cancer chemoresistance through paracrine osteopontin signaling.

The Journal of clinical investigation

Qian J, LeSavage BL, Hubka KM, Ma C, Natarajan S, Eggold JT, Xiao Y, Fuh KC, Krishnan V, Enejder A, Heilshorn SC, Dorigo O, Rankin EB

Active surveillance characterizes human intratumoral T cell exhaustion.

The Journal of clinical investigation

You R, Artichoker J, Fries A, Edwards AW, Combes AJ, Reeder GC, Samad B, Krummel MF

Interpreting and addressing suboptimal immune responses after COVID-19 vaccination in solid organ transplant recipients.

The Journal of clinical investigation

Stock PG, Henrich TJ, Segev DL, Werbel WA

Integrin a2ß1 regulates collagen I tethering to modulate hyperresponsiveness in reactive airway disease models.

The Journal of clinical investigation

Liu S, Ngo U, Tang XZ, Ren X, Qiu W, Huang X, DeGrado W, Allen CD, Jo H, Sheppard D, Sundaram AB

Melanocortin 4 receptor signals at the neuronal primary cilium to control food intake and body weight.

The Journal of clinical investigation

Wang Y, Bernard A, Comblain F, Yue X, Paillart C, Zhang S, Reiter JF, Vaisse C

Leveraging microenvironmental synthetic lethalities to treat cancer.

The Journal of clinical investigation

Metcalf KJ, Alazzeh A, Werb Z, Weaver VM

Immune checkpoint inhibitor-associated myocarditis: manifestations and mechanisms.

The Journal of clinical investigation

Moslehi J, Lichtman AH, Sharpe AH, Galluzzi L, Kitsis RN

Smoothened-activating lipids drive resistance to CDK4/6 inhibition in Hedgehog-associated medulloblastoma cells and preclinical models.

The Journal of clinical investigation

Daggubati V, Hochstetler J, Bommireddy A, Choudhury A, Krup AL, Choksi PK, Tong P, Li A, Xu L, Reiter JF, Raleigh DR

Natural killer cells activated through NKG2D mediate lung ischemia-reperfusion injury.

The Journal of clinical investigation

Calabrese DR, Aminian E, Mallavia B, Liu F, Cleary SJ, Aguilar OA, Wang P, Hoover J, Singer JP, Hays SR, Golden JA, Kukreja J, Dugger DT, Nakamura M, Lanier LL, Looney MR, Greenland JR

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