The Journal of clinical investigation

Skin microbiome and dermatologic disorders.

The Journal of clinical investigation

Scharschmidt TC, Segre JA

Monocytes and interstitial macrophages contribute to hypoxic pulmonary hypertension.

The Journal of clinical investigation

Kumar R, Nolan K, Kassa B, Chanana N, Palmo T, Sharma K, Singh K, Mickael C, Fonseca Balladares D, Nilsson J, Prabhakar A, Mishra A, Lee MH, Sanders L, Kumar S, Molofsky AB, Stenmark KR, Sheppard D, Tuder RM, Gupta MD, Thinlas T, Pasha Q, Graham BB

Disrupted callosal connectivity underlies long-lasting sensory-motor deficits in an NMDAreceptor antibody encephalitis mouse model.

The Journal of clinical investigation

Zhou J, Greenfield AL, Loudermilk RP, Bartley CM, Chen C, Chen X, Leroux MA, Lu Y, Necula D, Ngo TT, Tran BT, Honma PS, Lauderdale K, Zhao C, Zhou X, Wang H, Nicoll RA, Wang C, Paz JT, Palop JJ, Wilson MR, Pleasure SJ

Long COVID is associated with lower percentages of mature, cytotoxic NK cell phenotypes.

The Journal of clinical investigation

Tsao T, Buck AM, Grimbert L, LaFranchi BH, Altamirano Poblano B, Fehrman EA, Dalhuisen T, Hsue PY, Kelly JD, Martin JN, Deeks SG, Hunt PW, Peluso MJ, Aguilar OA, Henrich TJ

Endogenous antigens shape the transcriptome and TCR repertoire in an autoimmune arthritis model.

The Journal of clinical investigation

McCarthy EE, Yu S, Perlmutter N, Nakao Y, Naito R, Lin C, Riekher V, DeRisi J, Ye CJ, Weiss A, Ashouri JF

MGA loss-of-function variants cause premature ovarian insufficiency.

The Journal of clinical investigation

Tang S, Guo T, Song C, Wang L, Zhang J, Rajkovic A, Lin X, Chen S, Liu Y, Tian W, Wu B, Wang S, Wang W, Lai Y, Wang A, Xu S, Jin L, Ke H, Zhao S, Li Y, Qin Y, Zhang F, Chen ZJ

Sialylated glycoproteins suppress immune cell killing by binding to Siglec-7 and Siglec-9 in prostate cancer.

The Journal of clinical investigation

Wen RM, Stark JC, Marti GEW, Fan Z, Lyu A, Garcia Marques FJ, Zhang X, Riley NM, Totten SM, Bermudez A, Nolley R, Zhao H, Fong L, Engleman EG, Pitteri SJ, Bertozzi CR, Brooks JD

Neutrophil-specific Shp1 loss results in lethal pulmonary hemorrhage in mouse models of acute lung injury.

The Journal of clinical investigation

Moussavi-Harami SF, Cleary SJ, Magnen M, Seo Y, Conrad C, English BC, Qiu L, Wang KM, Abram CL, Lowell CA, Looney MR

Single-cell analysis of breast cancer metastasis reveals epithelial-mesenchymal plasticity signatures associated with poor outcomes.

The Journal of clinical investigation

Winkler J, Tan W, Diadhiou CM, McGinnis CS, Abbasi A, Hasnain S, Durney S, Atamaniuc E, Superville D, Awni L, Lee JV, Hinrichs JH, Wagner PS, Singh N, Hein MY, Borja M, Detweiler AM, Liu SY, Nanjaraj A, Sitarama V, Rugo HS, Neff N, Gartner ZJ, Oliveira Pisco A, Goga A, Darmanis S, Werb Z

CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target.

The Journal of clinical investigation

Le Q, Hadland B, Smith JL, Leonti A, Huang BJ, Ries R, Hylkema TA, Castro S, Tang TT, McKay CN, Perkins L, Pardo L, Sarthy J, Beckman AK, Williams R, Idemmili R, Furlan S, Ishida T, Call L, Srivastava S, Loeb AM, Milano F, Imren S, Morris SM, Pakiam F, Olson JM, Loken MR, Brodersen L, Riddell SR, Tarlock K, Bernstein ID, Loeb KR, Meshinchi S

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