Mechanisms underlying transcriptional dysregulation, DNA damage responses, inflammation and resistance. Design theranostics targeting the cancer surface proteome and define synthetic lethal interactions.
We leverage interdisciplinary approaches in bioengineering, endocrinology, and physiology to determine molecular mechanisms of tissue crosstalk in osteoarthritis.
We innovate new imaging methods and model systems to elucidate the cell and molecular biology of neurodegenerative diseases and the role of microglia.
Mentorship Development:
2/2021 - Three Truths & Three Tries: Facing & Overcoming Critical Social Justice Challenges at the Micro, Mezzo & Macro Levels
5/2021 - Sharpening your Mentoring Skills (SyMS)
7/2021 - Career Conversations
5/2022 - PSPG Faculty Community Circle
10-11/2023 - UCSF Inclusive Mentor/Manager Training
The Corces Lab studies the genetic and epigenetic underpinnings of neurodegenerative diseases using primary human tissue, multi-omic profiling, and large-scale functional genomics assays.
Mentorship Development:
11/2020 - Optimizing the Efficiency of Your Lab
2/2021 - Three Truths and Three Tries: Facing and Overcoming Critical Social Justice Challenges at the Micro, Mezzo, and Macro Levels
5/2021 - Sharpening your Mentoring Skills (SyMS)
9/2021 - Neuroscience Graduate Program - Disabilities Awareness Training
6/2022 - Career Conversations
10-11/2023 - UCSF Inclusive Mentor/Manager Training
The research interest of my lab lies at the intersection of CRISPR-based genome editing and protein/cell engineering with special focus on hematopoietic stem cells and red blood cell disorders.
