Defining conserved mechanisms regulating stem cell behavior and how these are altered with age and in response to chronic or acute changes in metabolism.
We develop and apply innovative approaches, such as CRISPR-based functional genomics, in human iPSC-derived neurons and glia and mouse models to elucidate mechanisms and therapeutic strategies for neurodegenerative diseases.
Mentorship Development:
4/12/19 Acknowleding and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab (Mission Bay)
4/30/20 Mental Health in a Pandemic: Q&A for Faculty
6/10/20 Tools and Tips for Virtual Learning
10/22/20 Gathering in Community: a Training for Faculty and Staff
9/11/20 Mentoring Across Differences
9/24/20 DEI Champions Training
Pathophysiology of Neurodegenerative Diseases: Aging, Stress, Lysosomes and Protein Homeostasis.
Mentorship Development:
4/26/19 Sharpening your Mentoring Skills (SyMS) with Sharon Milgram (Mission Bay)
11/23/20 Building Community in the UCSF MSTP
9/11/20 Mentoring Across Differences
2/18/21 Three Truths and Three Tries: Facing and Overcoming Critical Social Justice Challenges at the Micro, Mezzo, and Macro Levels
Development of gene therapy, oncolytic virotherapy, and immunotherapy for translational application to cancer (particularly CNS tumors), and genetic engineering strategies for regenerative medicine.
The Kattah Lab studies how intestinal epithelial cells contribute to IBD using mouse models, patient biopsies, and organoids. The ultimate goal is to develop precision treatments for patients.
Mechanisms Guiding Epithelial Organogenesis and Tissue Regeneration
Mentorship Development:
4/12/19 Acknowleding and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab (Parnassus)
5/2021 - Sharpening your Mentoring Skills (SyMS)
