Maya Kotas, MD, PhD

Asst Professor In Residence
Medicine
[email protected]
Research Description: 

Dr. Kotas is an Assistant Professor in the Division of Pulmonary, Critical Care, Sleep, Allergy and Sleep Medicine. She received her BA, MD and PhD from Yale University. After completing residency training in Internal Medicine at New York Presbyterian - Columbia University, she completed a fellowship in Pulmonary & Critical Care Medicine at UCSF. She serves as an attending physician in the intensive care units at UCSF.

Dr. Kotas's research focuses on the role of the innate immune system in regulating the biology of the airway epithelium. Her work utilizes mouse modeling and patient samples to better understand how the immune system reshapes the cells that line the airway during allergic diseases. The goal of this work is to discover new targets for treatment of allergic airway diseases.

Primary Thematic Area: 
Immunology
Secondary Thematic Area: 
Tissue / Organ Biology & Endocrinology
Research Summary: 
coordination of lung/airway tissue biology and defense through cooperation between the immune system and airway epithelial cells
Publications: 

Group 2 innate lymphoid cells promote inhibitory synapse development and social behavior.

Science (New York, N.Y.)

Barron JJ, Mroz NM, Taloma SE, Dahlgren MW, Ortiz-Carpena JF, Keefe MG, Escoubas CC, Dorman LC, Vainchtein ID, Chiaranunt P, Kotas ME, Nowakowski TJ, Bender KJ, Molofsky AB, Molofsky AV

Group 2 innate lymphoid cells constrain type 3/17 lymphocytes in shared stromal niches to restrict liver fibrosis.

bioRxiv : the preprint server for biology

Sbierski-Kind J, Cautivo KM, Wagner JC, Dahlgren MW, Nilsson J, Krasilnikov M, Mroz NM, Lizama CO, Gan AL, Matatia PR, Taruselli MT, Chang AA, Caryotakis S, O'Leary CE, Kotas M, Mattis AN, Peng T, Locksley RM, Molofsky AB

Interleukin-13 associated epithelial remodeling correlates with clinical severity in nasal polyposis.

The Journal of allergy and clinical immunology

Kotas ME, Patel NN, Cope EK, Gurrola JG, Goldberg AN, Pletcher SD, Seibold MA, Moore CM, Gordon ED

Tuft Cells: Context- and Tissue-Specific Programming for a Conserved Cell Lineage.

Annual review of pathology

Kotas ME, O'Leary CE, Locksley RM

Injury-induced pulmonary tuft cells are heterogenous, arise independent of key Type 2 cytokines, and are dispensable for dysplastic repair.

eLife

Barr J, Gentile ME, Lee S, Kotas ME, Fernanda de Mello Costa M, Holcomb NP, Jaquish A, Palashikar G, Soewignjo M, McDaniel M, Matsumoto I, Margolskee R, Von Moltke J, Cohen NA, Sun X, Vaughan AE