We study how organisms interact with the environment -- more specifically, what happens when there are variations in oxygen levels in the atmosphere or vitamin/cofactor levels in the diet.
We are interested in the mechanisms underlying normal development of the nervous system and use that information to gain insights about the cellular and molecular causes of neurological disorders, and the regulation of axon and dendrite regeneration.
We investigate molecular mechanisms that contribute to the development and progression of head and neck cancer, and seek to develop novel therapeutic agents for this disease
Defining conserved mechanisms regulating stem cell behavior and how these are altered with age and in response to chronic or acute changes in metabolism.
We develop and apply innovative approaches, such as CRISPR-based functional genomics, in human iPSC-derived neurons and glia and mouse models to elucidate mechanisms and therapeutic strategies for neurodegenerative diseases.
Mentorship Development:
4/12/19 Acknowleding and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab (Mission Bay)
4/30/20 Mental Health in a Pandemic: Q&A for Faculty
6/10/20 Tools and Tips for Virtual Learning
10/22/20 Gathering in Community: a Training for Faculty and Staff
9/11/20 Mentoring Across Differences
9/24/20 DEI Champions Training
