Hua Su, MD

Professor
Anesthesia
[email protected]
+1 415 476-0141
Research Description: 

My research interests include: (1) adeno-associated viral vector (AAV)-mediated tissue specific gene transfer and gene expression; (2) the pathogenesis of cerebrovascular malformation; (3) development of new therapies for ischemic stroke and arteriovenous malformation; and (4) the impact of aging, peripheral injury (such as bone fracture), and innate immune response on stroke recovery.

Primary Thematic Area: 
Vascular & Cardiac Biology
Secondary Thematic Area: 
Neurobiology
Research Summary: 
My research is focused on uncovering the mechanisms and development of new therapies for the cerebrovascular diseases including brain vascular malformations, stroke, and cognitive dysfunction.

Websites

Publications: 

Abstract WP28: Can the reduction of mutant endothelial cells hold promise for treating brain arteriovenous malformation?.

Stroke

Zahra Shabani nabikandi, Leandro Prado, sonali shaligram, Rui Zhang, Wan Zhu, Rich Liang, Alka Yadav, Calvin Wang, Hua Su

Abstract WP34: Targeted delivery of therapeutic genes into brain endothelial cells for treating brain AVMs.

Stroke

Alka Yadav, Rich Liang, kelly press, Annika Schmidt, Zahra Shabani nabikandi, Kun Leng, Calvin Wang, Abinav Sekhar, Joshua Shi, Garth Devlin, Trevor Gonzalez, Aravind Asokan, Hua Su

Increasing Endoglin Deletion in Endothelial Cells Exacerbates the Severity of Brain Arteriovenous Malformation in Mouse.

Biomedicines

Shabani Z, Do Prado LB, Zhang R, Zhu W, Shaligram SS, Yadav A, Wang C, Su H

Evaluation of AAV Capsids and Delivery Approaches for Hereditary Hemorrhagic Telangiectasia Gene Therapy.

Translational stroke research

Yadav A, Liang R, Press K, Schmidt A, Shabani Z, Leng K, Wang C, Sekhar A, Shi J, Devlin GW, Gonzalez TJ, Asokan A, Su H