eLife

PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis.

eLife

Yamaguchi N, Weinberg EM, Nguyen A, Liberti MV, Goodarzi H, Janjigian YY, Paty PB, Saltz LB, Kingham TP, Loo JM, Stanchina E, Tavazoie SF

mTORC1 in the orbitofrontal cortex promotes habitual alcohol seeking.

eLife

Nadege Morisot, Khanhky Phamluong, Yann Ehinger, Anthony L Berger, Jeffrey J Moffat, Dorit Ron

mTORC1 in the orbitofrontal cortex promotes habitual alcohol seeking.

eLife

Morisot N, Phamluong K, Ehinger Y, Berger AL, Moffat JJ, Ron D

CTCF confers local nucleosome resiliency after DNA replication and during mitosis.

eLife

Owens N, Papadopoulou T, Festuccia N, Tachtsidi A, Gonzalez I, Dubois A, Vandormael-Pournin S, Nora EP, Bruneau B, Cohen-Tannoudji M, Navarro P

The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins.

eLife

Ngo AM, Shurtleff MJ, Popova KD, Kulsuptrakul J, Weissman JS, Puschnik AS

A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS.

eLife

McMahon M, Contreras A, Holm M, Uechi T, Forester CM, Pang X, Jackson C, Calvert ME, Chen B, Quigley DA, Luk JM, Kelley RK, Gordan JD, Gill RM, Blanchard SC, Ruggero D

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