The Journal of clinical investigation

Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic beta cells.

The Journal of clinical investigation

Zhong L, Georgia S, Tschen SI, Nakayama K, Nakayama K, Bhushan A

A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia.

The Journal of clinical investigation

Steidl U, Steidl C, Ebralidze A, Chapuy B, Han HJ, Will B, Rosenbauer F, Becker A, Wagner K, Koschmieder S, Kobayashi S, Costa DB, Schulz T, O'Brien KB, Verhaak RG, Delwel R, Haase D, Trümper L, Krauter J, Kohwi-Shigematsu T, Griesinger F, Tenen DG

Sequential ABL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutations with altered oncogenic potency.

The Journal of clinical investigation

Shah NP, Skaggs BJ, Branford S, Hughes TP, Nicoll JM, Paquette RL, Sawyers CL

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons.

The Journal of clinical investigation

Claret M, Smith MA, Batterham RL, Selman C, Choudhury AI, Fryer LG, Clements M, Al-Qassab H, Heffron H, Xu AW, Speakman JR, Barsh GS, Viollet B, Vaulont S, Ashford ML, Carling D, Withers DJ

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance.

The Journal of clinical investigation

Babitt JL, Huang FW, Xia Y, Sidis Y, Andrews NC, Lin HY

Genomics and the evolution, pathogenesis, and diagnosis of tuberculosis.

The Journal of clinical investigation

Ernst JD, Trevejo-Nuñez G, Banaiee N

Genomics and the evolution, pathogenesis, and diagnosis of tuberculosis.

The Journal of clinical investigation

Ernst JD, Trevejo-Nuñez G, Banaiee N

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action.

The Journal of clinical investigation

Shu Y, Sheardown SA, Brown C, Owen RP, Zhang S, Castro RA, Ianculescu AG, Yue L, Lo JC, Burchard EG, Brett CM, Giacomini KM

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action.

The Journal of clinical investigation

Shu Y, Sheardown SA, Brown C, Owen RP, Zhang S, Castro RA, Ianculescu AG, Yue L, Lo JC, Burchard EG, Brett CM, Giacomini KM

Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus.

The Journal of clinical investigation

Erlebacher A, Vencato D, Price KA, Zhang D, Glimcher LH

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