Blood

Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia.

Blood

Kruth KA, Fang M, Shelton DN, Abu-Halawa O, Mahling R, Yang H, Weissman JS, Loh ML, Müschen M, Tasian SK, Bassik MC, Kampmann M, Pufall MA

Ventricular arrhythmias and sudden death in patients taking ibrutinib.

Blood

Lampson BL, Yu L, Glynn RJ, Barrientos JC, Jacobsen ED, Banerji V, Jones JA, Walewska R, Savage KJ, Michaud GF, Moslehi JJ, Brown JR

In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia.

Blood

Francis SS, Wallace AD, Wendt GA, Li L, Liu F, Riley LW, Kogan S, Walsh KM, de Smith AJ, Dahl GV, Ma X, Delwart E, Metayer C, Wiemels JL

In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia.

Blood

Francis SS, Wallace AD, Wendt GA, Li L, Liu F, Riley LW, Kogan S, Walsh KM, de Smith AJ, Dahl GV, Ma X, Delwart E, Metayer C, Wiemels JL

Tofacitinib Reverses Growth Promoting Effects of the Bone Marrow Stromal Environment Though Inhibition of JAK1/STAT3 Signaling in Multiple Myeloma.

Blood

Christine Lam, Megan Murnane, Geoffrey A. Smith, Jack Taunton, Blake T. Aftab, Arun P. Wiita

CD46 Is Amplified in High-Risk Myeloma with Gain of Chromosome 1q and Selectively Targeted By a Novel Anti-CD46 Antibody-Drug Conjugate.

Blood

Daniel W. Sherbenou, Blake T. Aftab, Yang Su, Christopher R. Behrens, Arun P. Wiita, Aaron C. Logan, Diego Acosta-Alvear, Byron C. Hann, Peter Walter, Xiaobo Wu, John P. Atkinson, Jeffrey L. Wolf, Thomas G. Martin, Bin Liu

Targeting NF-KB Activation in Novel Intracranial Models of CNS Lymphoma.

Blood

Huimin Geng, Huaxin Gao, Cigall Kadoch, Ming Lu, Lingjing Chen, Rana Anjum, Lisa Drew, Sebastien Degorce, Keith Dillman, Michele Mayo, Shawn Anderson, Colin Collins, Clifford A. Lowell, James L. Rubenstein

Resistant T-Cell Acute Lymphoblastic Leukemias That Emerge after In Vivo Treatment with Dexamethasone Frequently Down-Regulate Glucocorticoid Receptor Protein Expression.

Blood

Anica M. Wandler, Benjamin Huang, Alessandro Scacchetti, Jeff Craig, Hannah Yan, Gabriela Monsalve, Qing Li, Monique Dail, Jasmine C. Wong, Joy Nakitandwe, Olga Weinberg, Robert P. Hasserjian, Scott C. Kogan, Deepak Sampath, James R. Downing, Keith Yamamoto, Barry S. Taylor, Jon C. Aster, Jinghui Zhang, Kevin Shannon

Pml Nuclear Body Disruption Cooperates in APL Pathogenesis, Impacting DNA Damage Repair Pathways.

Blood

Edwige Voisset, Eva Moravcsik, Eva W Stratford, Amie Jaye, Christopher J Palgrave, Robert K Hills, Paolo Salomoni, Scott C. Kogan, Ellen Solomon, David Grimwade

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