Blood

Novel Allosteric Inhibitors of Heat Shock Protein 70 As Agents to Probe Protein Homeostasis and Overcome Proteasome Inhibitor Resistance in Multiple Myeloma.

Blood

Ian Ferguson, Christine Lam, Margarette C. Mariano, Donghui Wang, Paul Phojanakong, Sami Toumivaara, Hao Shao, Byron C Hann, Jason Gestwicki, Arun P Wiita

Integrating Phosphoproteomics and Transcriptional Classifiers Reveals "Hidden Signaling" in Multiple Myeloma Including Differential KRAS and NRAS Mutant Effects.

Blood

Yu-Hsiu T. Lin, Gergory P. Way, Margarette C. Mariano, Makeba Marcoulis, Ian Ferguson, Casey S. Greene, Arun P Wiita

IFITM3-Mediated Regulation of Cell Membrane Dynamics Is Essential for Malignant B-Cell Transformation.

Blood

Jae-Woong Lee, Huimin Geng, Derek S Dinson, Gang Xiao, Kadriye Nehir Cosgun, Lai N Chan, Zhengshan Chen, Michael Farzan, Jae U Jung, Arun P Wiita, Markus Muschen

Glucocorticoids Paradoxically Induce Intrinsic Steroid Resistance through a STAT5-Mediated Survival Mechanism in T-Cell Acute Lymphoblastic Leukemia.

Blood

Lauren K. Meyer, Benjamin Huang, Ritu Roy, Aaron Hechmer, Anica Wandler, Cristina Delgado-Martin, Adam B. Olshen, Terzah M. Horton, David T Teachey, Kevin M. Shannon, Michelle L. Hermiston

Children's Oncology Group (COG) AALL0434: Successful Disease Control without Cranial Radiation in Newly Diagnosed T Lymphoblastic Lymphoma (T-LL).

Blood

Robert James Hayashi, Stuart S. Winter, Kimberly P. Dunsmore, Meenakshi Devidas, Brent Wood, Michelle L. Hermiston, David T Teachey, Sherrie L. Perkins, Rodney R. Miles, Elizabeth A. Raetz, Mignon L. Loh, Naomi Winick, William L. Carroll, Stephen P. Hunger, Megan S. Lim, Catherine M. Bollard, Thomas G. Gross

Application of Hyperpolarized 13C Magnetic Resonance Imaging to Detect Target Inhibition of NFkB Activation in Preclinical Patient-Derived Models of CNS Lymphoma.

Blood

Huimin Geng, Brice Tiret, Hua-Xin Gao, Cigall Kadoch, Ming Lu, Lingjing Chen, Ilwoo Park, Gerd Melkus, Adam Elkhaled, John Kurhanewicz, Lisa Drew, Sebastien Degorce, Michele Mayo, Keith Dillman, Rana Anjum, Andrew Bloecher, Myriam Chaumeil, James Rubenstein

Identifying Factors in Multiple Myeloma Controlling Response to B-Cell Maturation Antigen (BCMA)-Targeted Immunotherapy Using CRISPR-Based Functional Genomics.

Blood

Poornima Ramkumar,Jaime Leong,Meghan Seyler,Stratton J Georgoulis,Axel Hyrenius Wittsten,Priya Choudhry,Kole Roybal,Arun P Wiita,Martin Kampmann

The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions.

Blood

Nagy Z, Vögtle T, Geer MJ, Mori J, Heising S, Di Nunzio G, Gareus R, Tarakhovsky A, Weiss A, Neel BG, Desanti GE, Mazharian A, Senis YA

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