bioRxiv

Stochastically Emergent Tumors offer in vivo whole genome interrogation of cancer evolution from non-malignant precursors

bioRxiv

Ruhollah Moussavi-Baygi, Matthew J. Ryan, Woogwang Sim, Samuel B. Hoelscher, Valbona Luga, Arun A. Chandrakumar, Lore Hoes, Junghwa Cha, Young Sun Lee, Katelyn Herm, Ben Doron, C.K. Cornelia Ding, Bradley A. Stohr, Peng Jin, Tejasveeta Nadkarni, Xiangyi Fang, Melita Haryono, An Nguyen, Wouter R. Karthaus, Charles Sawyers, Felix Y. Feng, Hani Goodarzi, Rohit Bose

Senescent fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity

bioRxiv

Jinyoung Lee, Soledad Reyes Nabora, Sang-Ho Woo, Sakshi Goel, Fia Stratton, Chaoyuan Kuang, Aaron Mansfield, Lindsay LaFave, Tien Peng

Compensatory epistasis maintains ACE2 affinity in SARS-CoV-2 Omicron BA.1

bioRxiv

Alief Moulana*, Thomas Dupic*, Angela M. Phillips*†, Jeffrey Chang*, Serafina Nieves, Anne A. Roffler, Allison J. Greaney, Tyler N. Starr, Jesse D. Bloom, Michael M. Desai†

GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans

bioRxiv

Nair KS, Srivastava C, Brown RV, Koli S, Choquet H, Kang HS, Kuo YM, Sutherland C, Grimm SA, Badea A, Zhao Y, Yin J, Okamoto K, Clark G, Borras T, Zode G, Chakrabarti S, Kizhatil K, John SW, Jorgenson E, and Jetten AM.

Distinct cellular immune signatures in acute Zika virus infection are associated with high or low persisting neutralizing antibody titers

bioRxiv

McCarthy EE, Odorizzi PM, Lutz E, Smullin CP, Stone M, Simmons G, Hunt PW, Feeney ME, Norris PJ, Busch MP, Spitzer MH*, Rutishauser RL*.

ACVR1R206H increases osteogenic/ECM gene expression and impairs myofiber formation in human skeletal muscle stem cells

bioRxiv

Barruet E, Garcia SM, Wu J, Morales BM, Tamaki S, Moody T, and Pomerantz JH.

Doxycycline Significantly Enhances Induction of iPSCs to Endoderm by Enhancing survival via AKT Phosphorylation

bioRxiv

Cristina Esteva-Font, Tao Su, Caitlin Peaslee, Caroline Duwaerts, Ke Liu, Marisa Medina, Jacquelyn J. Maher, Aras N. Mattis.

Hepatocyte-specific deletion of XBP1 sensitizes mice to liver injury through hyperactivation of IRE1a

bioRxiv

Duwaerts CC, Siao K, Soon RK, Her C, Iwawaki T, Kohno K, Mattis AN, Maher JJ.

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