Minnie Sarwal, MD, PhD

Professor In Residence
Primary Thematic Area
M_Surgery
Secondary Thematic Area
Research Summary
Organ transplant biology and immunology advances by the use of high throughput technologies using single-cell and single-nuclear RNASeq, T cell and B cell receptor sequencing, single-cell and phsopho-protoemics, CyTOF and spatial imaging.
+1 415 353-4043

The Sarwal Lab has been a pioneer in organ transplant biology and immunology advances by the use of high throughput technologies using single-cell and single-nuclear RNASeq, T cell and B cell receptor sequencing, single-cell and phsopho-protoemics, CyTOF and spatial imaging. The lab has had continuous funding from the NIH for over 25 years, initially at Stanford University and now at UCSF, in the Department of Surgery, Division of Multi-Organ Transplantation. The Sarwal Lab has also been recently funded by the Chang Zuckerberg Initiative to build the first normal kidney single cell atlas, in collaboration with Stanford, Harvard, the BROAD and Princeton. The lab is unique as it has a diverse group of dry and wet lab researchers and coordinator support and clinical trial access with real time recruitment of patients and biosamples from studies on kidney injury (such as FSGS, IgA), CMV and BK virus infection, and kidney/heart and lung transplantation. The Sarwal Lab provides deep training and exposure to translational research in kidney diseases, biomarker discovery and validation, novel drug design and repositioning and development of new computational tools for high-dimensional data analysis and integration. Minnie Sarwal, PI, is Co-Director of the T32 Training Grant in Transplant Surgery (FAVOR), Co-Director of the Kidney Pancreas Transplant Program at UCSF and is a Capstone Mentor for the Masters in Translational Medicine, UCSF/UC Berkeley.

Publications

Complete steroid avoidance is effective and safe in children with renal transplants: a multicenter randomized trial with three-year follow-up.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Sarwal MM, Ettenger RB, Dharnidharka V, Benfield M, Mathias R, Portale A, McDonald R, Harmon W, Kershaw D, Vehaskari VM, Kamil E, Baluarte HJ, Warady B, Tang L, Liu J, Li L, Naesens M, Sigdel T, Waskerwitz J, Salvatierra O