Neuro-oncology

NCOG-71. GENOME ASSOCIATIONS WITH NEUROCOGNITIVE OUTCOMES, CEREBRAL MICROBLEEDS (CMBS), AND BRAIN VOLUME AND WHITE MATTER (WM) CHANGES IN PEDIATRIC BRAIN TUMOR SURVIVORS.

Neuro-oncology

Cassie Kline, Schuyler Stoller, Lennox Byer, Caleb Edwards, Rachna Prasad, Joseph Torkildson, Karen Gauvain, David Samuel, Janine Lupo, Melanie Morrison, Elizabeth Tong, Solomiia Savchuk, Christian Rodrigo Ugaz Valencia, Andreas Rauschecker, Jeffrey Rudie, Thomas Hoffmann, Dena Dubal, Heather Fullerton, Sabine Mueller

TMOD-28. NEW APPROACHES FOR ELUCIDATING MEDULLOBLASTOMA DEVELOPMENT VIA HINDBRAIN BLASTOCYST COMPLEMENTATION.

Neuro-oncology

Christin Schmidt, Annika Carlson, William Weiss, Bjoern Schwer

Functional analysis of low-grade glioma genetic variants predicts key target genes and transcription factors.

Neuro-oncology

Manjunath M, Yan J, Youn Y, Drucker KL, Kollmeyer TM, McKinney AM, Zazubovich V, Zhang Y, Costello JF, Eckel-Passow J, Selvin PR, Jenkins RB, Song JS

A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR.

Neuro-oncology

Sievers P, Sill M, Schrimpf D, Stichel D, Reuss DE, Sturm D, Hench J, Frank S, Krskova L, Vicha A, Zapotocky M, Bison B, Castel D, Grill J, Debily MA, Harter PN, Snuderl M, Kramm CM, Reifenberger G, Korshunov A, Jabado N, Wesseling P, Wick W, Solomon DA, Perry A, Jacques TS, Jones C, Witt O, Pfister SM, von Deimling A, Jones DTW, Sahm F

LSD1 Inhibition in pHGG: The key to unleashing immunotherapy?

Neuro-oncology

Nicolaides TP, Hashizume R

Phase 0 and Window of Opportunity Clinical Trial Design in Neuro-Oncology: A RANO Review.

Neuro-oncology

Vogelbaum MA, Krivosheya D, Borghei-Razavi H, Sanai N, Weller M, Wick W, Soffietti R, Reardon DA, Aghi MK, Galanis E, Wen PY, van den Bent M, Chang S

European genetic ancestry associated with risk of childhood ependymoma.

Neuro-oncology

Zhang C, Ostrom QT, Hansen HM, Gonzalez-Maya J, Hu D, Ziv E, Morimoto L, de Smith AJ, Muskens IS, Kline CN, Vaksman Z, Hakonarson H, Diskin SJ, Kruchko C, Barnholtz-Sloan JS, Ramaswamy V, Ali-Osman F, Bondy ML, Taylor MD, Metayer C, Wiemels JL, Walsh KM

European genetic ancestry associated with risk of childhood ependymoma.

Neuro-oncology

Chenan Zhang, Quinn T Ostrom, Helen M Hansen, Julio Gonzalez-Maya, Donglei Hu, Elad Ziv, Libby Morimoto, Adam J de Smith, Ivo S Muskens, Cassie N Kline, Zalman Vaksman, Hakon Hakonarson, Sharon J Diskin, Carol Kruchko, Jill S Barnholtz-Sloan, Vijay Ramaswamy, Francis Ali-Osman, Melissa L Bondy, Michael D Taylor, Catherine Metayer, Joseph L Wiemels, Kyle M Walsh

Adult Diffuse Glioma GWAS by Molecular Subtype Identifies Variants in D2HGDH and FAM20C.

Neuro-oncology

Eckel-Passow JE, Drucker KL, Kollmeyer TM, Kosel ML, Decker PA, Molinaro AM, Rice T, Praska CE, Clark L, Caron A, Abyzov A, Batzler A, Song JS, Pekmezci M, Hansen HM, McCoy LS, Bracci PM, Wiemels J, Wiencke JK, Francis S, Burns TC, Giannini C, Lachance DH, Wrensch M, Jenkins RB

Recurrent tumor and treatment-induced effects have different MR signatures in contrast enhancing and non-enhancing lesions of high-grade gliomas.

Neuro-oncology

Cluceru J, Nelson SJ, Wen Q, Phillips JJ, Shai A, Molinaro AM, Alcaide-Leon P, Olson MP, Nair D, LaFontaine M, Chunduru P, Villanueva-Meyer JE, Cha S, Chang SM, Berger MS, Lupo JM

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