The Journal of biological chemistry

Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease.

The Journal of biological chemistry

Landles C, Sathasivam K, Weiss A, Woodman B, Moffitt H, Finkbeiner S, Sun B, Gafni J, Ellerby LM, Trottier Y, Richards WG, Osmand A, Paganetti P, Bates GP

Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease.

The Journal of biological chemistry

Landles C, Sathasivam K, Weiss A, Woodman B, Moffitt H, Finkbeiner S, Sun B, Gafni J, Ellerby LM, Trottier Y, Richards WG, Osmand A, Paganetti P, Bates GP

The ubiquitin ligase Nedd4-1 is required for heart development and is a suppressor of thrombospondin-1.

The Journal of biological chemistry

Fouladkou F, Lu C, Jiang C, Zhou L, She Y, Walls JR, Kawabe H, Brose N, Henkelman RM, Huang A, Bruneau BG, Rotin D

The ubiquitin ligase Nedd4-1 is required for heart development and is a suppressor of thrombospondin-1.

The Journal of biological chemistry

Fouladkou F, Lu C, Jiang C, Zhou L, She Y, Walls JR, Kawabe H, Brose N, Henkelman RM, Huang A, Bruneau BG, Rotin D

Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract.

The Journal of biological chemistry

Firtina Z, Danysh BP, Bai X, Gould DB, Kobayashi T, Duncan MK

Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract.

The Journal of biological chemistry

Firtina Z, Danysh BP, Bai X, Gould DB, Kobayashi T, Duncan MK

Transforming growth factor beta1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanism.

The Journal of biological chemistry

Roux J, Carles M, Koh H, Goolaerts A, Ganter MT, Chesebro BB, Howard M, Houseman BT, Finkbeiner W, Shokat KM, Paquet AC, Matthay MA, Pittet JF

Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection).

The Journal of biological chemistry

Roan NR, Sowinski S, Münch J, Kirchhoff F, Greene WC

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