Diabetes

Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians.

Diabetes

Hwang JY, Sim X, Wu Y, Liang J, Tabara Y, Hu C, Hara K, Tam CH, Cai Q, Zhao Q, Jee S, Takeuchi F, Go MJ, Ong RT, Ohkubo T, Kim YJ, Zhang R, Yamauchi T, So WY, Long J, Gu D, Lee NR, Kim S, Katsuya T, Oh JH, Liu J, Umemura S, Kim YJ, Jiang F, Maeda S, Chan JC, Lu W, Hixson JE, Adair LS, Jung KJ, Nabika T, Bae JB, Lee MH, Seielstad M, Young TL, Teo YY, Kita Y, Takashima N, Osawa H, Lee SH, Shin MH, Shin DH, Choi BY, Shi J, Gao YT, Xiang YB, Zheng W, Kato N, Yoon M, He J, Shu XO, Ma RC, Kadowaki T, Jia W, Miki T, Qi L, Tai ES, Mohlke KL, Han BG, Cho YS, Kim BJ

Metformin pharmacogenomics: current status and future directions.

Diabetes

Pawlyk AC, Giacomini KM, McKeon C, Shuldiner AR, Florez JC

Metformin pharmacogenomics: current status and future directions.

Diabetes

Pawlyk AC, Giacomini KM, McKeon C, Shuldiner AR, Florez JC

Chronological analysis with fluorescent timer reveals unique features of newly generated ß-cells.

Diabetes

Miyatsuka T, Matsuoka TA, Sasaki S, Kubo F, Shimomura I, Watada H, German MS, Hara M

Chronological analysis with fluorescent timer reveals unique features of newly generated ß-cells.

Diabetes

Miyatsuka T, Matsuoka TA, Sasaki S, Kubo F, Shimomura I, Watada H, German MS, Hara M

Diabetes irreversibly depletes bone marrow-derived mesenchymal progenitor cell subpopulations.

Diabetes

Januszyk M, Sorkin M, Glotzbach JP, Vial IN, Maan ZN, Rennert RC, Duscher D, Thangarajah H, Longaker MT, Butte AJ, Gurtner GC

Diabetes irreversibly depletes bone marrow-derived mesenchymal progenitor cell subpopulations.

Diabetes

Januszyk M, Sorkin M, Glotzbach JP, Vial IN, Maan ZN, Rennert RC, Duscher D, Thangarajah H, Longaker MT, Butte AJ, Gurtner GC

Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders.

Diabetes

Herold KC, Gitelman SE, Ehlers MR, Gottlieb PA, Greenbaum CJ, Hagopian W, Boyle KD, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, McNamara J, Bluestone JA

Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function.

Diabetes

Villalta SA, Lang J, Kubeck S, Kabre B, Szot GL, Calderon B, Wasserfall C, Atkinson MA, Brekken RA, Pullen N, Arch RH, Bluestone JA

Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation.

Diabetes

Jing E, O'Neill BT, Rardin MJ, Kleinridders A, Ilkeyeva OR, Ussar S, Bain JR, Lee KY, Verdin EM, Newgard CB, Gibson BW, Kahn CR

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