Blood

JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation.

Blood

Meyer L, Verbist KC, Albeituni S, Scull BP, Bassett R, Stroh AN, Tillman H, Allen CE, Hermiston M, Nichols KE

Excellent Outcomes Following Hematopoietic Cell Transplantation for Wiskott-Aldrich Syndrome: A PIDTC Report.

Blood

Burroughs L, Petrovic A, Brazauskas R, Liu X, Griffith LM, Ochs HD, Bleesing J, Edwards S, Dvorak CC, Chaudhury S, Prockop S, Quinones R, Goldman F, Quigg T, Chandrakasan S, Smith AR, Parikh SH, Dávila Saldaña BJ, Thakar MS, Phelan R, Shenoy S, Forbes LR, Martinez CA, Chellapandian D, Shereck E, Miller H, Kapoor N, Barnum JL, Chong H, Shyr D, Chen K, Abu-Arja RF, Shah A, Weinacht K, Moore TB, Joshi A, DeSantes K, Gillio AP, Cuvelier GDE, Keller MD, Rozmus J, Torgerson TR, Pulsipher MA, Haddad E, Sullivan K, Logan BR, Kohn DB, Puck JM, Notarangelo LD, Pai SY, Rawlings D, Cowan MJ

Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice.

Blood

Zambetti NA, Firestone AJ, Remsberg JR, Huang BJ, Wong JC, Long AM, Predovic M, Suciu RM, Inguva A, Kogan SC, Haigis KM, Cravatt BF, Shannon K

Emerging Mutations at Relapse in Patients with FLT3-Mutated Relapsed/Refractory Acute Myeloid Leukemia Who Received Gilteritinib Therapy in the Phase 3 Admiral Trial.

Blood

Catherine C. Smith, Mark J. Levis, Alexander E. Perl, Giovanni Martinelli, Andreas Neubauer, Ellin Berman, Pau Montesinos, Maria R. Baer, Richard A. Larson, Wen-Chien Chou, Hisayuki Yokoyama, Christian Recher, Sung-Soo Yoon, Jason E. Hill, Matt Rosales, Erkut Bahceci

Regulation of eIF4E Guides a Unique Translational Program to Steer Erythroid Maturation.

Blood

Craig M Forester, Gun Woo-Byeon, Juan Oses-Prieto, Al Burlingame, Maria Barna, Davide M Ruggero

Comprehensive Investigation of White Blood Cell and Gene Expression Profiles As Risk Factors for Multiple Myeloma in African Americans.

Blood

Linda Kachuri, Zhaohui Du, Niels Weinhold, Gregory Song, Kristin Alyse Rand, David Van Den Berg, Amie Hwang, Xin Sheng, Victor Hom, Sikander Ailawadhi, Ajay K Nooka, Seema Singhal, Edward S. Peters, Cathryn Bock, Ann Mohrbacher, Alexander Stram, Sonja I Berndt, William J. Blot, Esther M. John, Leslie Bernstein, Antoinette Stroup, Maurizio Zangari, Frits van Rhee, Andrew Olshan, Wei Zheng, Sue Ann Ingles, Michael Press, John David Carpten, Stephen J Chanock, Jayesh Mehta, Graham A Colditz, Jeffrey Wolf, Thomas G. Martin, Mark A. Fiala, Howard R. Terebelo, Nalini Janakiraman, Laurence Kolonel, Kenneth C. Anderson, Loic Le Marchand, Daniel Auclair, Brian C.-H. Chiu, Daniel Stram, Ravi Vij, Leon Bernal-Mizrachi, Gareth Morgan, Jeffrey A. Zonder, Carol Ann Huff, Sagar Lonial, Robert Z. Orlowski, David Conti, Christopher A. Haiman, Elad Ziv, John S Witte, Wendy Cozen

Association between a Polygenic Risk Score for Multiple Myeloma Risk and Overall Survival.

Blood

Alyssa I. Clay-Gilmour, Michelle Hildebrandt, Yan Asmann, Elizabeth E. Brown, Jonathan N Hofmann, John Spinelli, Graham Giles, Parveen Bhatti, Wendy Cozen, Dennis P. Robinson, Daniel R O'Brien, S. Vincent Rajkumar, Shulan Tian, Sonja I Berndt, Stephen J Chanock, Mitchell Machiela, Aaron D. Norman, Jason P Sinnwell, Xifeng Wu, Rosalie Griffin Waller, Roger L Milne, Susan L Slager, Shaji K. Kumar, Nicola J Camp, Elad Ziv, Celine M. Vachon

The Combination of Dexamethasone and Ruxolitinib Synergistically Attenuates Disease Manifestations in a Preclinical Model of Hemophagocytic Lymphohistiocytosis.

Blood

Lauren K. Meyer, Katherine Verbist, Sabrin Albeituni, Rachel Bassett, Michelle L. Hermiston, Kim E. Nichols

Protein Translocation Inhibitors Overcome Cytokine-Induced Glucocorticoid Resistance in T-Cell Acute Lymphoblastic Leukemia.

Blood

Lauren K. Meyer, Cristina Delgado-Martin, Phillip P. Sharp, Dustin McMinn, Christopher J. Kirk, Jack Taunton, Michelle L. Hermiston

Symptom Assessment in Patients with BCR-ABL-Negative Myeloproliferative Neoplasms at an Academic Medical Institution.

Blood

Kelly L. Schoenbeck, Miguel Carlos Cerejo, Patricia A. Cornett, Lloyd E. Damon, Karin L. Gaensler, Andrew D. Leavitt, Aaron C. Logan, Gabriel N. Mannis, Rebecca L. Olin, Giselle Salmasi, Peter H. Sayre, Neil P. Shah, Anand Dhruva, Chloe E. Atreya, Catherine C. Smith

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