Autophagy

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity.

Autophagy

Haller M, Hock AK, Giampazolias E, Oberst A, Green DR, Debnath J, Ryan KM, Vousden KH, Tait SW

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity.

Autophagy

Haller M, Hock AK, Giampazolias E, Oberst A, Green DR, Debnath J, Ryan KM, Vousden KH, Tait SW

Increased autophagy accelerates colchicine-induced muscle toxicity.

Autophagy

Ching JK, Ju JS, Pittman SK, Margeta M, Weihl CC

Increased autophagy accelerates colchicine-induced muscle toxicity.

Autophagy

Ching JK, Ju JS, Pittman SK, Margeta M, Weihl CC

I?B kinase complex (IKK) triggers detachment-induced autophagy in mammary epithelial cells independently of the PI3K-AKT-MTORC1 pathway.

Autophagy

Chen N, Debnath J

I?B kinase complex (IKK) triggers detachment-induced autophagy in mammary epithelial cells independently of the PI3K-AKT-MTORC1 pathway.

Autophagy

Chen N, Debnath J

The next generation proteasome inhibitors carfilzomib and oprozomib activate prosurvival autophagy via induction of the unfolded protein response and ATF4.

Autophagy

Zang Y, Thomas SM, Chan ET, Kirk CJ, Freilino ML, DeLancey HM, Grandis JR, Li C, Johnson DE

The next generation proteasome inhibitors carfilzomib and oprozomib activate prosurvival autophagy via induction of the unfolded protein response and ATF4.

Autophagy

Zang Y, Thomas SM, Chan ET, Kirk CJ, Freilino ML, DeLancey HM, Grandis JR, Li C, Johnson DE

Hypoxia-induced tumor cell autophagy mediates resistance to anti-angiogenic therapy.

Autophagy

Hu YL, Jahangiri A, De Lay M, Aghi MK

Hypoxia-induced tumor cell autophagy mediates resistance to anti-angiogenic therapy.

Autophagy

Hu YL, Jahangiri A, De Lay M, Aghi MK

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