Sheng Ding, PhD

William K. Bowes Jr. Distinguished Investigator
Professor
Department of Pharmaceutical Chemistry
+1 415 734-2717
Research Description: 

Dr. Sheng Ding is currently William K. Bowes, Jr. Distinguished Investigator and Professor at Gladstone Institute of Cardiovascular Disease, and Department of Pharmaceutical Chemistry, University of California San Francisco. He obtained his B.S. in chemistry with honors from Caltech in 1999, and a Ph.D. in chemistry from The Scripps Research Institute in 2003. Before moving to Gladstone/UCSF in early 2011, Ding was an Assistant Professor and then Associate Professor of Chemistry at Scripps from 2003 to 2011. Dr. Ding has pioneered on developing and applying innovative chemical approaches to stem cell biology and regeneration, with a focus on discovering and characterizing novel small molecules that can control various cell fate/function, including stem cell maintenance, activation, differentiation and reprogramming in various developmental stages and tissues. Ding has published over 100 research articles, reviews and book chapters, and made several seminal contributions to the stem cell field. Ding is a cofounder of Fate Therapeutics and Stemgent.

Primary Thematic Area: 
Developmental & Stem Cell Biology
Secondary Thematic Area: 
Cancer Biology & Cell Signaling
Research Summary: 
Our lab develops and uses chemical biology approaches to identify and characterize novel small molecules that modulate cell fate and function in normal or diseased states.
Publications: 

Abstract 11415: Enhancing Direct Cardiac Reprogramming Efficiency Using Small Molecules.

Circulation

Tamer M Mohamed, Nicole Stone, Emily Berry, Haixia Wang, Sheng Ding, Deepak Srivastava

458. Sensitizing Ovarian Cancer Cells To Chemotherapy By Interfering With Pathways That Are Involved in the Formation and Maintenance of Cancer Stem Cells.

Molecular Therapy

Kamola Saydaminova, Robert Strauss, Min Xie, Charles Dreshner, Sheng Ding, Andre Lieber

Chapter 4 Chemical Approaches to Controlling Cell Fate.

Principles of Developmental Genetics

Mingliang Zhang, Ke Li, Min Xie, Sheng Ding

Small Molecules in Cellular Reprogramming and Differentiation.

Epigenetics and Disease

Xu Yuan, Wenlin Li, Sheng Ding

Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins.

Cell stem cell

Hongyan Zhou, Shili Wu, Jin Young Joo, Saiyong Zhu, Dong Wook Han, Tongxiang Lin, Sunia Trauger, Geoffery Bien, Susan Yao, Yong Zhu, Gary Siuzdak, Hans R. Schöler, Lingxun Duan, Sheng Ding