Ryan Hernandez, PhD

Vice Dean & Professor
Department of Bioengineering and Therapeutic Sciences
+1 415 514-9813
Research Overview: 

Hernandez Lab research focuses on three main areas:

  1. Basic population genomics: we seek to use current patterns of human genetic variation from whole genome sequencing to understand the evolutionary history of human populations.
  2. Disease susceptibility in complex populations: We strive to leverage evolutionary signals in patterns of genetic variation to uncover the meaningful associations with phenotypic variation.
  3. Host-pathogen interactions: We develop tools to leverage patterns of genetic diversity within populations and divergence across phylogenies to learn more about the genetic targets of host-pathogen interactions.
Primary Thematic Area: 
Human Genetics
Secondary Thematic Area: 
None
Research Summary: 
We study patterns of human genetic variation using large-scale data and the tools of population genomics.
Mentorship Development: 

3/10/20    Promoting Student Mental Health:A Presentation and Discussion (Staff and Faculty)    
4/23/20    Effective Strategies for IDPs    
4/30/20    Mental Health in a Pandemic: Q&A for Faculty    
2/18/21    Three Truths and Three Tries: Facing and Overcoming Critical Social Justice Challenges at the Micro, Mezzo, and Macro Levels    
2/19/21    DEI Champions Training

Publications: 

Effect of different ankle joint positions on medial gastrocnemius muscle fiber strains during isometric plantarflexion.

Scientific reports

Cunnane BT, Sinha U, Malis V, Hernandez RD, Smitaman E, Sinha S

The Urinary Metabolomic Fingerprint in Extremely Preterm Infants on Total Parenteral Nutrition vs. Enteral Feeds.

Metabolites

Guardado M, Steurer M, Chapin C, Hernandez RD, Ballard PL, Torgerson D

Efficacy of National Comprehensive Cancer Network Guidelines in Identifying Pathogenic Germline Variants Among Unselected Patients with Prostate Cancer: The PROCLAIM Trial.

European urology oncology

Shore N, Gazi M, Pieczonka C, Heron S, Modh R, Cahn D, Belkoff LH, Berger A, Mazzarella B, Veys J, Idom C, Morris D, Jayram G, Engelman A, Bukkapatnam R, Dato P, Bevan-Thomas R, Cornell R, Wise DR, Hardwick MK, Hernandez RD, Rojahn S, Layman P, Hatchell KE, Heald B, Nussbaum RL, Nielsen SM, Esplin ED

The hydrocortisone-responsive urinary metabolome of premature infants.

Pediatric research

Torgerson D, Guardado M, Steurer M, Chapin C, Hernandez RD, Ballard PL

Effect of Ocrelizumab on B- and T-Cell Receptor Repertoire Diversity in Patients With Relapsing Multiple Sclerosis From the Randomized Phase III OPERA Trial.

Neurology(R) neuroimmunology & neuroinflammation

Laurent SA, Strauli NB, Eggers EL, Wu H, Michel B, Demuth S, Palanichamy A, Wilson MR, Sirota M, Hernandez RD, Cree BAC, Herman AE, von Büdingen HC