Ryan Hernandez, PhD

Professor
Department of Bioengineering and Therapeutic Sciences
[email protected]
+1 415 514-9813
Research Overview: 

Hernandez Lab research focuses on three main areas:

  1. Basic population genomics: we seek to use current patterns of human genetic variation from whole genome sequencing to understand the evolutionary history of human populations.
  2. Disease susceptibility in complex populations: We strive to leverage evolutionary signals in patterns of genetic variation to uncover the meaningful associations with phenotypic variation.
  3. Host-pathogen interactions: We develop tools to leverage patterns of genetic diversity within populations and divergence across phylogenies to learn more about the genetic targets of host-pathogen interactions.
Primary Thematic Area: 
Human Genetics
Secondary Thematic Area: 
None
Research Summary: 
We study patterns of human genetic variation using large-scale data and the tools of population genomics.
Mentorship Development: 

3/2020 - Promoting Student Mental Health:A Presentation and Discussion (Staff and Faculty)    
4/2020 - Effective Strategies for IDPs    
4/2020 - Mental Health in a Pandemic: Q&A for Faculty    
2/2021 - Three Truths and Three Tries: Facing and Overcoming Critical Social Justice Challenges at the Micro, Mezzo, and Macro Levels    
2/2021 - DEI Champions Training
2/2021 - UCSF School of Medicine Differences Matter Initiative
10/2021 - Sharpening Your Research Mentoring Skills
5/2022 - Dis/ability Awareness Training
11/2022 - ...Inclusively: Why, How & Right Bleeping Now
11/2022 - Faculty Development Training: INclusivity is a Design Question. Which Practices Will You Use?
4/2024 - Supporting Learners in Distress

Publications: 

Urinary Acetaminophen Metabolites and Clinical Outcomes in Extremely Premature Infants.

American journal of perinatology

Guardado M, Torgerson D, Chapin C, Atum A, Hernandez RD, Clyman R, Simmons R, Parry S, Ballard PL

Genetics of Latin American Diversity Project: Insights into population genetics and association studies in admixed groups in the Americas.

Cell genomics

Borda V, Loesch DP, Guo B, Laboulaye R, Veliz-Otani D, French JN, Leal TP, Gogarten SM, Ikpe S, Gouveia MH, Mendes M, Abecasis GR, Alvim I, Arboleda-Bustos CE, Arboleda G, Arboleda H, Barreto ML, Barwick L, Bezzera MA, Blangero J, Borges V, Caceres O, Cai J, Chana-Cuevas P, Chen Z, Custer B, Dean M, Dinardo C, Domingos I, Duggirala R, Dieguez E, Fernandez W, Ferraz HB, Gilliland F, Guio H, Horta B, Curran JE, Johnsen JM, Kaplan RC, Kelly S, Kenny EE, Konkle BA, Kooperberg C, Lescano A, Lima-Costa MF, Loos RJF, Manichaikul A, Meyers DA, Naslavsky MS, Nickerson DA, North KE, Padilla C, Preuss M, Raggio V, Reiner AP, Rich SS, Rieder CR, Rienstra M, Rotter JI, Rundek T, Sacco RL, Sanchez C, Sankaran VG, Santos-Lobato BL, Schumacher-Schuh AF, Scliar MO, Silverman EK, Sofer T, Lasky-Su J, Tumas V, Weiss ST, Latin American Research Consortium on the Genetics of Parkinson’s Disease (LARGE-PD), National Institute of Neurological Disorders and Stroke (NINDS) Stroke Genetics Network (SiGN) Conso, Trans-Omics for Precision Medicine (TOPMed) Population Genetics Working Group, Mata IF, Hernandez RD, Tarazona-Santos E, O'Connor TD

PROPEL: a scalable model for postbaccalaureate training to promote diversity in the biomedical workforce.

Journal of microbiology & biology education

Allen J, Abdiwahab E, Morris MD, Le Saux CJ, Betancur P, Ansel KM, Hernandez RD, Nystul TG

py_ped_sim - A flexible forward genetic simulator for complex family pedigree analysis.

bioRxiv : the preprint server for biology

Guardado M, Perez C, Jackson S, Magaña J, Campana S, Samperio E, Rojas BC, Hernandez S, Syas K, Hernandez R, Zavala EI, Rohlfs R

Effect of different ankle joint positions on medial gastrocnemius muscle fiber strains during isometric plantarflexion.

Scientific reports

Cunnane BT, Sinha U, Malis V, Hernandez RD, Smitaman E, Sinha S