Nadav Ahituv, PhD

Professor
Department of Bioengineering and Therapeutic Sciences
+1 415 476-1838
Research Description: 

The Ahituv lab is focused on identifying gene regulatory elements and linking nucleotide variation within them to various phenotypes including morphological differences between species, drug response and human disease. In addition, our lab is developing massively parallel reporter assays (MPRAs) that allow for high-throughput functional characterization of gene regulatory elements and the use of gene regulatory elements as therapeutic targets or disease diagnostic markers.

Primary Thematic Area: 
Human Genetics
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Gene regulation and human disease
Mentorship Development: 

4/2019 - Acknowledging and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab
4/2019 - Sharpening your Mentoring Skills (SyMS) with Sharon Milgram
6/2020 - Your Role in Workplace Diversity
10/2020 - DEI Champion Training
2/2021 - Three Truths & Three Tries: Facing & Overcoming Critical Social Justice Challenges at the Micro, Mezzo & Macro Levels

Websites

Publications: 

Cellular and transcriptional diversity over the course of human lactation.

Proceedings of the National Academy of Sciences of the United States of America

Nyquist SK, Gao P, Haining TKJ, Retchin MR, Golan Y, Drake RS, Kolb K, Mead BE, Ahituv N, Martinez ME, Shalek AK, Berger B, Goods BA

Massively parallel reporter perturbation assays uncover temporal regulatory architecture during neural differentiation.

Nature communications

Kreimer A, Ashuach T, Inoue F, Khodaverdian A, Deng C, Yosef N, Ahituv N

High-throughput characterization of the role of non-B DNA motifs on promoter function.

Cell genomics

Georgakopoulos-Soares I, Victorino J, Parada GE, Agarwal V, Zhao J, Wong HY, Umar MI, Elor O, Muhwezi A, An JY, Sanders SJ, Kwok CK, Inoue F, Hemberg M, Ahituv N

Ancestry- and sex-specific effects underlying inguinal hernia susceptibility identified in a multiethnic genome-wide association study meta-analysis.

Human molecular genetics

Choquet H, Li W, Yin J, Bradley R, Hoffmann TJ, Nandakumar P, 23andMe Research Team, Mostaedi R, Tian C, Ahituv N, Jorgenson E

COVID-19 mRNA Vaccination in Lactation: Assessment of Adverse Events and Vaccine Related Antibodies in Mother-Infant Dyads.

Frontiers in immunology

Golan Y, Prahl M, Cassidy AG, Gay C, Wu AHB, Jigmeddagva U, Lin CY, Gonzalez VJ, Basilio E, Chidboy MA, Warrier L, Buarpung S, Li L, Murtha AP, Asiodu IV, Ahituv N, Flaherman VJ, Gaw SL