Mazen Kheirbek, PhD

Associate Professor
Department of Psychiatry
Research Overview: 

Our primary goal is to delineate the neuronal circuits that generate emotional behavior. In particular, we are interested in those circuits that are disrupted in mood and anxiety-related disorders. We apply novel technologies to both monitor and control genetically identified neural networks in real time.

Primary Thematic Area: 
Secondary Thematic Area: 
Research Summary: 
Neural circuits for emotional behaviors
Mentorship Development: 

9/11/20    Mentoring Across Differences


Featured Publications: 

Distinct Contribution of Adult-Born Hippocampal Granule Cells to Context Encoding.


Danielson NB, Kaifosh P, Zaremba JD, Lovett-Barron M, Tsai J, Denny CA, Balough EM, Goldberg AR, Drew LJ, Hen R, Losonczy A, Kheirbek MA

Dendritic inhibition in the hippocampus supports fear learning.

Science (New York, N.Y.)

Lovett-Barron M, Kaifosh P, Kheirbek MA, Danielson N, Zaremba JD, Reardon TR, Turi GF, Hen R, Zemelman BV, Losonczy A

Differential control of learning and anxiety along the dorsoventral axis of the dentate gyrus.


Kheirbek MA, Drew LJ, Burghardt NS, Costantini DO, Tannenholz L, Ahmari SE, Zeng H, Fenton AA, Hen R

Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders.

Nature neuroscience

Kheirbek MA, Klemenhagen KC, Sahay A, Hen R

NR2B-dependent plasticity of adult-born granule cells is necessary for context discrimination.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Kheirbek MA, Tannenholz L, Hen R