Luke Gilbert, PhD

Asst Professor in Residence
Department of Urology
+1 415 476-9791
Research Overview: 

The Gilbert lab's expertise is in synthetic biology, functional genomics and cancer biology. We use genome scale screens, genetic interaction mapping and genome engineering to model and map the genetic and epigenetic causes underlying why some patients are cured and others are not by cancer therapy. 

Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
Human Genetics
Research Summary: 
The Gilbert lab's expertise is in synthetic biology, functional genomics and cancer biology.
Mentorship Development: 

4/26/19    Sharpening your Mentoring Skills (SyMS) with Sharon Milgram (Mission Bay)
12/12/19    ACRA: Setting Training Expectations for Trainees on the Academic Career Track (1.5 hours)
4/23/20    Effective Strategies for IDPs
10/20/20    Gathering in Community: a Training for Faculty and Staff

Featured Publications: 

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation.

eLife

Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.

Cell

Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.

Cell

Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N, Brandman O, Whitehead EH, Doudna JA, Lim WA, Weissman JS, Qi LS