Lani Wu, PhD

Professor
Pharmaceutical Chemistry
+1 415 502-3196
Research Description: 

Dr. Lani Wu is interested in discovering principles underlying cellular individuality, the emergence of collective cellular behaviors, and the evolution of drug resistance. She also applies the high-throughput technology developed by her laboratory to diverse applications, including mapping paths of signal transduction and accelerating drug discovery. Prior to arriving at UCSF, Dr. Wu has worked at the UT Southwestern, Harvard University, Rosetta Informatics, Microsoft, and Princeton University.

Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
None
Research Summary: 
Investigate how complex biological networks regulate precise cellular behaviors and how dis-regulation leads to disease.
Publications: 

Loss of TET2 Affects Proliferation and Drug Sensitivity through Altered Dynamics of Cell-State Transitions.

Cell systems

Morinishi L, Kochanowski K, Levine RL, Wu LF, Altschuler SJ

Generation and Quantitative Imaging of Enteroid Monolayers.

Methods in molecular biology (Clifton, N.J.)

Sanman LE, Chen IW, Bieber JM, Thorne CA, Wu LF, Altschuler SJ

A multi-modal data resource for investigating topographic heterogeneity in patient-derived xenograft tumors.

Scientific data

Rajaram S, Roth MA, Malato J, VandenBerg S, Hann B, Atreya CE, Altschuler SJ, Wu LF