Kevan Shokat, PhD

Professor
Cellular Molecular Pharmacology
[email protected]
+1 415 514-0472
Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
Neurobiology
Research Summary: 
The Shokat lab uses chemical genetics to study and target signaling proteins, with the aim of finding new ways to treat human diseases.
Publications: 

IL-13 and IL-17A Activate β1 Integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to Enhance Force Transmission in Airway Smooth Muscle.

bioRxiv : the preprint server for biology

Ngo U, Shi Y, Woodruff P, Shokat K, DeGrado W, Jo H, Sheppard D, Sundaram AB

Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D.

Nature chemical biology

Zheng Q, Zhang Z, Guiley KZ, Shokat KM

Nanomolar Protein Thermal Profiling with Modified Cyanine Dyes.

Analytical chemistry

Malakoutikhah M, Mahran R, Gooran N, Masoumi A, Lundell K, Liljeblad A, Guiley K, Dai S, Zheng Q, Zhu L, Shokat KM, Kopra K, Härmä H

Selective activation of intracellular β1AR using a spatially restricted antagonist.

bioRxiv : the preprint server for biology

Liccardo F, Morstein J, Lin TY, Pampel J, Shokat KM, Irannejad R

Protocol for performing and optimizing differential scanning fluorimetry experiments.

STAR protocols

Wu T, Hornsby M, Zhu L, Yu JC, Shokat KM, Gestwicki JE