Kevan Shokat, PhD

Professor
Cellular Molecular Pharmacology
[email protected]
+1 415 514-0472
Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
Neurobiology
Research Summary: 
The Shokat lab uses chemical genetics to study and target signaling proteins, with the aim of finding new ways to treat human diseases.
Publications: 

Deazaguanylation is a nucleobase-protein conjugation required for type IV CBASS immunity.

bioRxiv : the preprint server for biology

Wassarman DR, Pfaff P, Paulo JA, Gygi SP, Shokat KM, Kranzusch PJ

HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma.

Cancer research

Turnham RE, Pitea A, Jang GM, Xu Z, Lim HC, Choi AL, Von Dollen J, Levin RS, Webber JT, McCarthy E, Hu J, Li X, Che L, Singh A, Yoon A, Chan G, Kelley RK, Swaney DL, Zhang W, Bandyopadhyay S, Theis FJ, Eckhardt M, Chen X, Shokat KM, Ideker T, Krogan NJ, Gordan JD

Direct RAS inhibitors turn 10.

Nature chemical biology

Ostrem JML, Peters U, Shokat KM

Subcellular activation of β-adrenergic receptors using a spatially restricted antagonist.

Proceedings of the National Academy of Sciences of the United States of America

Liccardo F, Morstein J, Lin TY, Pampel J, Lang D, Shokat KM, Irannejad R