Eric Collisson, MD

Associate Professor
Department of Medicine
+1 415 353-9888
Research Overview: 

My laboratory uses a variety of techniques to interrogate three basic themes in the biology and clinical behavior of these deadly cancers: (1) intra- patient tumor heterogeneity at the temporal and anatomic levels, (2) inter-patient heterogeneity between different patients, and (3) tumor-microenvironmental interactions. We use a combination of genetically engineered mouse models, cell lines, and clinically derived samples to interrogate multiple genomic outputs with a focus on genomic DNA and mRNA.

Primary Thematic Area: 
Cancer Biology & Cell Signaling
Secondary Thematic Area: 
Human Genetics
Research Summary: 
I am a medical oncologist with a specific interest in the genomics of cancer.

Websites

Publications: 

Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix.

The Journal of clinical investigation

Jiang H, Torphy RJ, Steiger K, Hongo H, Ritchie AJ, Kriegsmann M, Horst D, Umetsu SE, Joseph NM, McGregor K, Pishvaian MJ, Blais EM, Lu B, Li M, Hollingsworth M, Stashko C, Volmar K, Yeh JJ, Weaver VM, Wang ZJ, Tempero MA, Weichert W, Collisson EA

Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma.

Nature communications

Cao W, Lee H, Wu W, Zaman A, McCorkle S, Yan M, Chen J, Xing Q, Sinnott-Armstrong N, Xu H, Sailani MR, Tang W, Cui Y, Liu J, Guan H, Lv P, Sun X, Sun L, Han P, Lou Y, Chang J, Wang J, Gao Y, Guo J, Schenk G, Shain AH, Biddle FG, Collisson E, Snyder M, Bivona TG

Distinctions with a Difference: RNA Subtyping and Clinical Outcome In Pancreatic Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Collisson EA

Estimation of Fractional Extracellular Space at CT for Predicting Chemotherapy Response and Survival in Pancreatic Ductal Adenocarcinoma.

AJR. American journal of roentgenology

Wang ZJ, Zhang TT, An C, Ko AH, Tempero M, Collisson E, Yeh BM

Theranostic targeting of CUB domain containing protein 1 (CDCP1) in pancreatic cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Moroz A, Wang YH, Sharib JM, Wei J, Zhao N, Huang Y, Chen Z, Martinko AJ, Zhou J, Lim SA, Zhang LH, Seo Y, Carlin S, Leung KK, Collisson EA, Kirkwood KS, Wells JA, Evans MJ