Ananya Krishnapura & Patrick Kennedy

Ananya Krishnapura (student)

"A novel role for tRNA modification in CD8+ T cell-mediated antitumor immunity"

Miao S, Li H, et al. tRNA m1A modification regulates cholesterol biosynthesis to promote antitumor immunity of CD8+ T cells. J Exp Med. 2025 Mar 3;222(3):e20240559. doi: 10.1084/jem.20240559. Epub 2025 Jan 28. PMID: 39873720; PMCID: PMC11774205

Coaches: Mark Ansel, PhD and Chris Allen, PhD

Patrick Kennedy (student)

"Signaling Cross-Talk in T Cells: Lessons from Germline G Protein Mutations"

Hyoungjun Ham et al., Germline mutations in a G protein identify signaling cross-talk in T cells. Science 385, eadd8947 (2024). DOI: 10.1126/science.add8947

Coaches: Harish Vasudevan, MD, PhD and Julia Carnevale, PhD

Moderator: Emily Chen & Simon Wong

Location: HSW-302, Parnassus & MH-1405, Mission Bay